Varshney Rajeev K, Graner Andreas, Sorrells Mark E
Institute of Plant Genetics and Crop Plant Research (IPK), Corrensstrasse 3, D-06466 Gatersleben, Germany.
Trends Plant Sci. 2005 Dec;10(12):621-30. doi: 10.1016/j.tplants.2005.10.004. Epub 2005 Nov 14.
Genomics research is generating new tools, such as functional molecular markers and informatics, as well as new knowledge about statistics and inheritance phenomena that could increase the efficiency and precision of crop improvement. In particular, the elucidation of the fundamental mechanisms of heterosis and epigenetics, and their manipulation, has great potential. Eventually, knowledge of the relative values of alleles at all loci segregating in a population could allow the breeder to design a genotype in silico and to practice whole genome selection. High costs currently limit the implementation of genomics-assisted crop improvement, particularly for inbreeding and/or minor crops. Nevertheless, marker-assisted breeding and selection will gradually evolve into 'genomics-assisted breeding' for crop improvement.
基因组学研究正在产生新的工具,如功能分子标记和信息学,以及有关统计学和遗传现象的新知识,这些可能会提高作物改良的效率和精准度。特别是,杂种优势和表观遗传学基本机制的阐明及其调控具有巨大潜力。最终,了解群体中所有分离位点上等位基因的相对值,可能使育种者能够在计算机上设计基因型并进行全基因组选择。目前,高成本限制了基因组学辅助作物改良的实施,特别是对于自花授粉作物和/或小众作物。尽管如此,标记辅助育种和选择将逐渐演变成用于作物改良的“基因组学辅助育种”。