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一项关于新生儿男性包皮环切术中疼痛缓解的视频研究。

A video study of pain relief during newborn male circumcision.

作者信息

Garry D J, Swoboda E, Elimian A, Figueroa R

机构信息

Department of Obstetrics, Gynecology and Reproductive Medicine, Stony Brook University, Stony Brook, NY, USA.

出版信息

J Perinatol. 2006 Feb;26(2):106-10. doi: 10.1038/sj.jp.7211413.

Abstract

OBJECTIVE

The purpose of this investigation was to compare the effectiveness of dorsal penile nerve block and topical lidocaine-prilocaine anesthesia techniques for pain relief during circumcision.

METHODS

In total, 18 healthy term newborn males were divided based on anesthesia. The topical lidocaine-prilocaine group had six males undergoing circumcision and three males undergoing a sham procedure. The dorsal penile nerve block group had six males undergoing circumcision and three males undergoing a sham procedure. The procedures were videotaped and viewed by 90 noninvestigator reviewers who scored the infants' pain using the Neonatal Infant Pain Scale and a numeric pain scale. Statistical analysis utilized a P-value of <0.05 as significant.

RESULTS

The median Neonatal Infant Pain Scale and numeric pain scores were significantly lower in the dorsal penile nerve block group than in the topical lidocaine-prilocaine group or the sham group (Neonatal Infant Pain Scale: 1.0 (range 0-6) versus 6.0 (range 2-6) versus 4.0 (range 0-6), P < 0.001, respectively; numeric pain scale: 2.0 (range 0-10) versus 8.0 (range 1-10) versus 4.0 (range 0-10), P < 0.001, respectively). In the sham group, procedures with the dorsal penile nerve block had significantly lower pain scores than those with topical lidocaine-prilocaine (Neonatal Infant Pain Scale: 1.0 (range 0-6) versus 5.0 (range 2- 6), P < 0.001; numeric pain scale: 1.0 (0-8) versus 6.0 (range 0-10), P < 0.001). When reviewers were divided by medical background, gender or parental status, no differences in pain scores were observed.

CONCLUSION

The dorsal penile nerve block anesthesia technique for newborn male circumcision was significantly more effective for pain relief than topical lidocaine-prilocaine.

摘要

目的

本研究旨在比较阴茎背神经阻滞和复方利多卡因局部麻醉技术在包皮环切术中缓解疼痛的效果。

方法

总共18名足月健康男婴根据麻醉方式分组。复方利多卡因局部麻醉组有6名男婴接受包皮环切术,3名男婴接受假手术。阴茎背神经阻滞组有6名男婴接受包皮环切术,3名男婴接受假手术。手术过程被录像,90名非研究人员观看录像,并使用新生儿疼痛量表和数字疼痛量表对婴儿的疼痛进行评分。统计分析以P值<0.05为有统计学意义。

结果

阴茎背神经阻滞组的新生儿疼痛量表中位数和数字疼痛评分显著低于复方利多卡因局部麻醉组或假手术组(新生儿疼痛量表:分别为1.0(范围0 - 6)、6.0(范围2 - 6)、4.0(范围0 - 6),P < 0.001;数字疼痛量表:分别为2.0(范围0 - 10)、8.0(范围1 - 10)、4.0(范围0 - 10),P < 0.001)。在假手术组中,阴茎背神经阻滞手术的疼痛评分显著低于复方利多卡因局部麻醉手术(新生儿疼痛量表:1.0(范围0 - 6)对5.0(范围2 - 6),P < 0.001;数字疼痛量表:1.0(0 - 8)对6.0(范围0 - 10),P < 0.001)。当根据医学背景、性别或父母状况对观察者进行分组时,未观察到疼痛评分的差异。

结论

对于新生儿男性包皮环切术,阴茎背神经阻滞麻醉技术在缓解疼痛方面比复方利多卡因局部麻醉显著更有效。

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