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经皮髓内减压、刮除术及医用硫酸钙颗粒移植治疗儿童单房性骨囊肿:一种新的微创技术。

Percutaneous intramedullary decompression, curettage, and grafting with medical-grade calcium sulfate pellets for unicameral bone cysts in children: a new minimally invasive technique.

作者信息

Dormans John P, Sankar Wudbhav N, Moroz Leslie, Erol Bülent

机构信息

Children's Hospital of Philadelphia, Wood Building, Philadelphia, PA 19104, USA.

出版信息

J Pediatr Orthop. 2005 Nov-Dec;25(6):804-11. doi: 10.1097/01.bpo.0000184647.03981.a5.

Abstract

Several treatment options exist for unicameral bone cysts (UBCs), including observation, steroid injection, bone marrow injection, and curettage and bone grafting. These are all associated with high recurrence rates, persistence, and occasional complications. Newer techniques have been described, most with variable success and only short follow-up reported. Because of these factors, a new minimally invasive percutaneous technique was developed for the treatment of UBCs in children. Twenty-eight children with UBCs who underwent percutaneous intramedullary decompression, curettage, and grafting with medical-grade calcium sulfate (MGCS) pellets by the senior author (J.P.D.) between April 2000 and April 2003 were analyzed as part of a pediatric musculoskeletal tumor registry at a large tertiary children's hospital. Four patients were lost to follow-up, and the remaining 24 patients had an average follow-up of 21.9 months (range 4-48 months). Twelve patients were followed for at least 24 months. Six of the 24 children had received previous treatment of their UBC, most often at an outside institution. Follow-up was performed through clinical evaluation and radiographic review. Postoperative radiographs at most recent follow-up showed complete healing, defined as more than 95% opacification, in 22 of 24 patients (91.7%). One patient (4.2%) demonstrated partial healing, defined as 80% to 95% opacification. One patient had less than 80% radiographic healing (4.2%). All 24 patients returned to full activities and were asymptomatic at most recent follow-up. The only complication noted was a superficial suture abscess that occurred in one patient; this resolved with local treatment measures. The new minimally invasive technique of percutaneous intramedullary decompression, curettage, and grafting with MGCS pellets demonstrates favorable results with low complication and recurrence rates compared with conventional techniques. The role of intramedullary decompression as a part of this percutaneous technique is discussed.

摘要

单房性骨囊肿(UBC)有多种治疗选择,包括观察、类固醇注射、骨髓注射以及刮除和植骨。这些方法都与高复发率、持续存在以及偶尔出现的并发症相关。已有一些新技术被描述,但大多数效果不一,且报道的随访时间较短。由于这些因素,一种新的微创经皮技术被开发用于治疗儿童UBC。作为一家大型三级儿童医院小儿肌肉骨骼肿瘤登记处的一部分,对2000年4月至2003年4月间由资深作者(J.P.D.)采用经皮髓内减压、刮除并植入医用级硫酸钙(MGCS)颗粒治疗UBC的28名儿童进行了分析。4例患者失访,其余24例患者的平均随访时间为21.9个月(范围4 - 48个月)。12例患者的随访时间至少为24个月。24名儿童中有6名曾接受过UBC的先前治疗,大多是在外部机构。通过临床评估和影像学检查进行随访。在最近一次随访时的术后X线片显示,24例患者中有22例(91.7%)完全愈合,定义为骨密度增高超过95%。1例患者(4.2%)显示部分愈合,定义为骨密度增高80%至95%。1例患者的X线愈合率低于80%(4.2%)。所有24例患者在最近一次随访时均恢复了全部活动且无症状。唯一记录到的并发症是1例患者出现了浅表缝线脓肿;经局部治疗措施后得以解决。与传统技术相比,经皮髓内减压、刮除并植入MGCS颗粒的新微创技术显示出良好的效果,并发症和复发率较低。本文讨论了髓内减压作为这种经皮技术一部分的作用。

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