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单房性骨囊肿的治疗:多种方法的对比研究。

Treatment of unicameral bone cyst: a comparative study of selected techniques.

机构信息

Department of Orthopaedics, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

J Bone Joint Surg Am. 2010 Apr;92(4):855-62. doi: 10.2106/JBJS.I.00607.

Abstract

BACKGROUND

There is a variety of treatment modalities for unicameral bone cysts, with variable outcomes reported in the literature. Although good initial outcomes have been reported, the success rate has often changed with longer-term follow-up. We introduce a novel, minimally invasive treatment method and compare its clinical outcomes with those of other methods of treatment of this lesion.

METHODS

From February 1994 to April 2008, forty patients with a unicameral bone cyst were treated with one of four techniques: serial percutaneous steroid and autogenous bone-marrow injection (Group 1, nine patients); open curettage and grafting with a calcium sulfate bone substitute either without instrumentation (Group 2, twelve patients) or with internal instrumentation (Group 3, seven patients); or minimally invasive curettage, ethanol cauterization, disruption of the cystic boundary, insertion of a synthetic calcium sulfate bone-graft substitute, and placement of a cannulated screw to provide drainage (Group 4, twelve patients). Success was defined as radiographic evidence of a healed cyst or of a healed cyst with some defect according to the modified Neer classification, and failure was defined as a persistent or recurrent cyst that needed additional treatment. Patients who sustained a fracture during treatment were also considered to have had a failure. The outcome parameters included the radiographically determined healing rate, the time to solid union, and the total number of procedures needed.

RESULTS

The follow-up time ranged from eighteen to eighty-four months. Group-4 patients had the highest radiographically determined healing rate. Healing was seen in eleven of the twelve patients in that group compared with three of the nine in Group 1, eight of the twelve in Group 2, and six of the seven in Group 3. Group-4 patients also had the shortest mean time to union: 3.7 +/- 2.3 months compared with 23.4 +/- 14.9, 12.2 +/- 8.5, and 6.6 +/- 4.3 months in Groups 1, 2, and 3, respectively.

CONCLUSIONS

This new minimally invasive method achieved a favorable outcome, with a higher radiographically determined healing rate and a shorter time to union. Thus, it can be considered an option for initial treatment of unicameral bone cysts.

摘要

背景

单发性骨囊肿有多种治疗方式,文献中报告的结果各不相同。虽然初始结果良好,但随着随访时间的延长,成功率往往会发生变化。我们介绍一种新的微创治疗方法,并将其与该病变的其他治疗方法的临床结果进行比较。

方法

从 1994 年 2 月至 2008 年 4 月,采用四种技术之一治疗 40 例单发性骨囊肿患者:连续经皮类固醇和自体骨髓注射(第 1 组,9 例);开放性刮除和硫酸钙骨替代物移植,不使用器械(第 2 组,12 例)或使用内部器械(第 3 组,7 例);或微创刮除、乙醇烧灼、破坏囊肿边界、插入合成硫酸钙骨替代物,并放置套管螺钉以提供引流(第 4 组,12 例)。成功定义为根据改良 Neer 分类,影像学显示囊肿愈合或愈合后存在一定缺陷;失败定义为需要额外治疗的持续性或复发性囊肿。治疗过程中发生骨折的患者也被认为治疗失败。观察指标包括影像学确定的愈合率、骨愈合时间和所需的总手术次数。

结果

随访时间为 18 至 84 个月。第 4 组患者的影像学愈合率最高。该组 12 例患者中有 11 例愈合,而第 1 组 9 例中有 3 例、第 2 组 12 例中有 8 例、第 3 组 7 例中有 6 例。第 4 组患者的平均愈合时间最短:3.7 ± 2.3 个月,而第 1、2 和 3 组分别为 23.4 ± 14.9、12.2 ± 8.5 和 6.6 ± 4.3 个月。

结论

这种新的微创方法取得了良好的效果,影像学确定的愈合率更高,愈合时间更短。因此,它可以被认为是治疗单发性骨囊肿的初始选择。

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