溶瘤病毒与肿瘤之战的最新进展

Recent progress in the battle between oncolytic viruses and tumours.

作者信息

Parato Kelley A, Senger Donna, Forsyth Peter A J, Bell John C

机构信息

Centre for Cancer Therapeutics, Ottawa Health Research Institute, 503 Smyth Road, Ottawa, Ontario, Canada K1H 8L6.

出版信息

Nat Rev Cancer. 2005 Dec;5(12):965-76. doi: 10.1038/nrc1750.

DOI:10.1038/nrc1750

PMID:16294217

Abstract

In the past 5 years, the field of oncolytic virus research has matured significantly and is moving past the stage of being a laboratory novelty into a new era of preclinical and clinical trials. What have recent anticancer trials of oncolytic viruses taught us about this exciting new line of therapeutics?

摘要

在过去的5年里，溶瘤病毒研究领域已显著成熟，正从实验室新奇事物阶段迈入临床前和临床试验的新时代。最近的溶瘤病毒抗癌试验让我们对这一令人兴奋的新治疗方法有了哪些了解？