Marbella Anne M, Yang Hongyan, Guse Clare E, Meurer John R, Layde Peter M
Injury Research Center, Medical College of Wisconsin, Department of Family and Community Medicine, Milwaukee 53226, USA.
WMJ. 2005 Sep;104(7):59-64.
This study investigates the Wisconsin adolescent self-poisoning problem, using state discharge data on medication-related self-inflicted injuries, focusing on medications used and risk factors.
Wisconsin inpatient discharge files for 3 years (January 1, 2000-December 31, 2002) were evaluated. Medication-related injuries were analyzed for intentionality, medications used, discharge status, and risk factors such as mental illness, eating disorders, and alcohol abuse or dependence.
There were nearly 3000 medication-related injury hospitalizations--1150 of them self-poisoning hospitalizations--among Wisconsin 12-17 year olds during 2000-2002. Females 12-17 years had twice as many medication-related injuries as males. Sixty percent of medication-related injuries occurred in patients with a mental disorder diagnosis. Non-narcotic analgesics were most commonly used and had one of the highest rates of intentionality (65%). A large proportion of intentional/suicidal medication-related injuries were discharged to another facility (35%), compared to 14% among all medical injuries. Males with medication-related injuries were twice (95% CI: 1.60, 2.75) as likely and females 1.4 (95% CI: 1.2, 1.6) times as likely to have intentional/suicidal injuries if they also abused or depended on alcohol.
Given that a nonfatal suicide attempt is the strongest predictor of eventual suicide, the hundreds of self-poisoning discharges per year in Wisconsin 12-17 year olds is a serious public health concern. Both the medical community and public health community should heed the warnings of these nonfatal suicide attempts and implement educational programs addressing this issue.
本研究利用与药物相关的自我伤害的州出院数据,调查威斯康星州青少年自我中毒问题,重点关注所使用的药物和风险因素。
对威斯康星州3年(2000年1月1日至2002年12月31日)的住院患者出院档案进行评估。分析与药物相关的伤害的意图、所使用的药物、出院状态以及精神疾病、饮食失调和酒精滥用或依赖等风险因素。
在2000 - 2002年期间,威斯康星州12至17岁青少年中,有近3000例与药物相关的伤害住院病例,其中1150例为自我中毒住院病例。12至17岁的女性与药物相关的伤害病例是男性的两倍。60%的与药物相关的伤害发生在患有精神障碍诊断的患者中。非麻醉性镇痛药使用最为普遍,且意图率最高(65%)之一。与所有医疗伤害中14%的比例相比,很大一部分故意/自杀性与药物相关的伤害患者被转至另一家机构(35%)。如果同时滥用或依赖酒精,与药物相关伤害的男性发生故意/自杀性伤害的可能性是普通男性的两倍(95%可信区间:1.60, 2.75),女性则为1.4倍(95%可信区间:1.2, 1.6)。
鉴于非致命自杀未遂是最终自杀的最强预测因素,威斯康星州12至17岁青少年每年数百例自我中毒出院病例是一个严重的公共卫生问题。医学界和公共卫生界都应留意这些非致命自杀未遂的警示,并实施针对该问题的教育项目。