Resta O, Bonfitto P, Sabato R, De Pergola G, Barbaro M P Foschino
Department of Clinical Methodology and Medical-Surgery Technology, University of Bari, Italy.
Diabetes Nutr Metab. 2004 Oct;17(5):296-303.
Obesity is a well known risk factor for obstructive sleep apnoea (OSA). Previous studies have investigated the prevalence of OSA among obese people, but a sample of women was rarely studied.
To describe the anthropometric and polysomnographic characteristics of a sample of obese women and investigate the effect of menopause on the prevalence of OSA.
Using a full-night polysomnography we studied a sample of 133 obese women with a body mass index (BMI) > or = 30 kg/m2.
About 44% of our sample had a respiratory disturbance index (RDI) > or = 10. Neck circumference, BMI and age resulted the strongest predictors of RDI value. We also found that the prevalence of OSA was higher among post-menopausal women (67%) in comparison with pre-menopausal women (31%). Moreover, post-menopausal women had larger neck circumference and higher waist-to-hip circumference ratio (WHR).
Among post-menopausal obese women the prevalence of OSA increases. We suggest that menopause could cause a different body fat distribution with an increase of fat in upper parts of the body and, consequently, with an increase of neck circumference.
肥胖是阻塞性睡眠呼吸暂停（OSA）的一个众所周知的危险因素。以往的研究调查了肥胖人群中OSA的患病率，但很少对女性样本进行研究。
描述肥胖女性样本的人体测量学和多导睡眠图特征，并研究绝经对OSA患病率的影响。
我们使用全夜多导睡眠图研究了133名体重指数（BMI）≥30 kg/m²的肥胖女性样本。
我们样本中约44%的人呼吸紊乱指数（RDI）≥10。颈围、BMI和年龄是RDI值最强的预测因素。我们还发现，绝经后女性中OSA的患病率（67%）高于绝经前女性（31%）。此外，绝经后女性的颈围更大，腰臀比（WHR）更高。
绝经后肥胖女性中OSA的患病率增加。我们认为，绝经可能导致身体脂肪分布不同，上半身脂肪增加，从而导致颈围增加。
