Fomda Bashir Ahmad, Thokar Manzoor Ahmad, Farooq Umar, Sheikh Asadullah
Department of Microbiology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar - Kashmir.
Indian J Pathol Microbiol. 2004 Jul;47(3):435-7.
The present study was conducted to determine the seroprevalence of rubella in pregnant women in Kashmir. One thousand nine hundred and eighteen pregnant women in age group of 20-35 were divided into two groups. Group I (n=892) consisted of women with previous history of repeated abortion (507), single abortion (220), intrauterine death (149), stillbirth (14) and premature delivery (2). Group II (n=1028) pregnant women with previous normal delivery. A total of 1918 pregnant women were screened for rubella IgM antibodies out of which 16.74% were positive. In women with bad obstetric history (Group I) 26.12% were positive as compared to 8.96% in women with no significant obstetric history (Group II). The IgM antibody positivity was higher in women with previous history of intrauterine death (IUD) 58.38% followed by stillbirth 57.14%, premature delivery 50%, abortion 21.8% and recurrent abortion 17.55%. The high prevalence of disease in this region demands urgent needs for prevention. Moreover antenatal cases should be screened as early diagnosis and time intervention will help in proper management of these cases.
本研究旨在确定克什米尔地区孕妇风疹的血清流行率。1918名年龄在20 - 35岁的孕妇被分为两组。第一组(n = 892)包括有反复流产史(507例)、单次流产史(220例)、宫内死亡史(149例)、死产史(14例)和早产史(2例)的女性。第二组(n = 1028)为既往有正常分娩史的孕妇。对总共1918名孕妇进行了风疹IgM抗体筛查,其中16.74%呈阳性。有不良产科史的女性(第一组)中26.12%呈阳性,而无明显产科史的女性(第二组)中这一比例为8.96%。既往有宫内死亡史(IUD)的女性中IgM抗体阳性率更高,为58.38%,其次是死产史女性,为57.14%,早产史女性为50%,流产史女性为21.8%,反复流产史女性为17.55%。该地区疾病的高流行率迫切需要预防。此外,应尽早对产前病例进行筛查,因为早期诊断和及时干预将有助于对这些病例进行妥善管理。