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[长春市地区孕妇病毒感染的血清流行病学调查]

[Sero-epidemiological survey of virus infections in pregnant women of the Changchun district].

作者信息

Yue J

机构信息

Bethune Medical University, Changchun.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1990 Sep;25(5):269-71, 315.

PMID:2178080
Abstract

ELISA method was used to detect Rubella virus specific IgG in serum for 315 pregnant women. Susceptible cases with negative IgG was found in 8.9% (28/315) and recently infected cases was found in 6.0% (19/315). Serum CMV-IgG was assayed for 476 pregnant women. Forty-two cases (8.8%) were found to be negative. The cord serum CMV-IgM positive rate was 2.3% (6/259). Serum Herpes Simplex virus (HSV) IgG was assayed in 384 pregnant women. The negative rate for Type II virus was 26.8% (103/384) and that for Type II virus was 18.0% (53/295). In the cord serum the HSV-Type II and Type IgM was positive each in one case among 212 newborn babies. The results of this preliminary survey indicate that the sero-immunologic estimation of specific globulin is helpful in early detection of intrauterine infection.

摘要

采用酶联免疫吸附测定法检测315名孕妇血清中的风疹病毒特异性IgG。IgG阴性的易感病例占8.9%(28/315),近期感染病例占6.0%(19/315)。检测了476名孕妇的血清巨细胞病毒IgG。发现42例(8.8%)呈阴性。脐血血清巨细胞病毒IgM阳性率为2.3%(6/259)。检测了384名孕妇血清中的单纯疱疹病毒(HSV)IgG。II型病毒阴性率为26.8%(103/384),I型病毒阴性率为18.0%(53/295)。在212名新生儿的脐血血清中,II型和I型HSV IgM各有1例呈阳性。这项初步调查结果表明,特异性球蛋白的血清免疫学评估有助于早期发现宫内感染。

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