Sekiguchi Goro
Tokyo Metropolitan Center for Oral Health of Persons with Disabilities, Tokyo.
No To Hattatsu. 2005 Nov;37(6):512-6.
We studied pitting of the dental enamel in cases of tuberous sclerosis complex (TSC), by staining defect sites. Many pits were found in the enamel of the TSC patients, especially on the labial surface of the incisors. Although the pathogenesis is unclear, pits of this type have been reported in TSC patients, but in the author's experience, have never been observed in cases of other diseases. On the basis of the results in this study and those previously published, we conclude that dental enamel pitting is a finding which suggests the diagnosis of TSC.
我们通过对牙釉质缺损部位进行染色，研究了结节性硬化症（TSC）患者的牙釉质凹陷情况。在TSC患者的牙釉质中发现了许多凹陷，尤其是在门牙的唇面。尽管发病机制尚不清楚，但这种类型的凹陷在TSC患者中已有报道，不过根据作者的经验，在其他疾病患者中从未观察到过。基于本研究结果以及先前发表的结果，我们得出结论，牙釉质凹陷是提示TSC诊断的一个表现。
