Mlynarczyk G
Ann N Y Acad Sci. 1991;615:367-9. doi: 10.1111/j.1749-6632.1991.tb37783.x.
Dental enamel pitting as a diagnostic sign of tuberous sclerosis (TSC) is explored and a protocol for the oral examination of patients and individuals at risk is described. In the study, 50 patients with TSC and 250 control patients were examined for dental enamel pitting. A simple clinical protocol was established for examination using a dental disclosing solution swabbed on dry teeth. The incidence of enamel pitting in the adult dentition of patients with TSC was 100%, whereas that in the adult dentition of the control group was 7%. The simplicity of the test and the high probability of occurrence in TSC make it an important tool in the diagnosis of this serious genetic disease.
探讨了牙釉质凹陷作为结节性硬化症（TSC）的诊断标志，并描述了对患者及有患病风险个体进行口腔检查的方案。在该研究中，对50例TSC患者和250例对照患者进行了牙釉质凹陷检查。建立了一种简单的临床检查方案，即使用牙用显示剂擦拭干燥牙齿。TSC患者恒牙列中牙釉质凹陷的发生率为100%，而对照组恒牙列中的发生率为7%。该检查的简便性以及在TSC中出现的高概率使其成为诊断这种严重遗传病的重要工具。
