对不同青霉素耐药水平的非产青霉素酶淋病奈瑟菌菌株的遗传变异性分析。
Analysis of genetic variability of penicillinase non-producing Neisseria gonorrhoeae strains with different levels of resistance to penicillin.
作者信息
de la Fuente L, Vázquez J A
机构信息
Servicio de Bacteriología, Centro Nacional de Microbiologia, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
出版信息
J Med Microbiol. 1992 Aug;37(2):96-9. doi: 10.1099/00222615-37-2-96.
Genetic variability among 41 penicillinase non-producing Neisseria gonorrhoeae strains, isolated in Spain, with different levels of resistance to penicillin was investigated by multilocus enzyme electrophoresis. Based on the results obtained by analysis at seven enzyme loci, the strains were separated into 17 electrophoretic types. The average number of alleles/enzyme locus was 2.85; the mean genetic diversity/locus was 0.49 for individual isolates and 0.516 for electrophoretic types. The results showed that these gonococcal strains were, genetically, a highly variable group of organisms.
通过多位点酶电泳研究了在西班牙分离出的41株不产生青霉素酶的淋病奈瑟菌菌株之间的遗传变异性，这些菌株对青霉素具有不同程度的耐药性。根据在7个酶位点分析获得的结果，这些菌株被分为17种电泳类型。每个酶位点的等位基因平均数为2.85；单个分离株的平均基因多样性/位点为0.49，电泳类型的平均基因多样性/位点为0.516。结果表明，这些淋球菌菌株在遗传上是一组高度可变的生物体。
Zotero 插件