Khan Abdus Sattar, Shah Said Alam
Department of Chemistry, University of Peshawar.
J Pak Med Assoc. 2005 Oct;55(10):420-3.
To evaluate the significance of serum ferritin in iron deficiency anaemia as compared to other indices.
Children were selected as anaemic and non-anaemic on the basis of hemoglobin (10g/dl) and transferrin saturation (15%). Red cell morphology, hemoglobin, serum iron, TIBC, transferrin saturation and serum ferritin were determined.
Red cell morphology was of little significance. Haemoglobin, serum iron, transferrin saturation and serum ferritrin were all lower in children. A positive correlation of serum ferritin with age, haemoglobin, serum iron and transferrin saturation and a negative correlation with TIBC was found.
Serum ferritin was more sensitive indicator as compared to serum iron, TIBC, and transferrin saturation.
评估血清铁蛋白在缺铁性贫血中相较于其他指标的意义。
根据血红蛋白（10g/dl）和转铁蛋白饱和度（15%）将儿童分为贫血组和非贫血组。测定红细胞形态、血红蛋白、血清铁、总铁结合力、转铁蛋白饱和度和血清铁蛋白。
红细胞形态意义不大。儿童的血红蛋白、血清铁、转铁蛋白饱和度和血清铁蛋白均较低。发现血清铁蛋白与年龄、血红蛋白、血清铁和转铁蛋白饱和度呈正相关，与总铁结合力呈负相关。
与血清铁、总铁结合力和转铁蛋白饱和度相比，血清铁蛋白是更敏感的指标。
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