Jamali Niaz Hussain, Jamali Abdul Hakeem, Khand Aftab Ahmed, Mahesar Hidayatullah, Arain Muhammad Iqbal
Institute of Pharmaceutical Sciences, Peoples University of Medical and Health Sciences for WomenNawabshah (SBA), Pakistan.
Department of Physiology, University of Sindh JamshoroPakistan.
Am J Blood Res. 2017 Jun 15;7(3):18-28. eCollection 2017.
Ferritin is a protein found in reticuloendothelial system and does not work only as a mid-size protein during Hemoglobin synthesis but also as storage protein for iron delivery. This cross sectional study was conducted in District Shaheed Benazirabad during the period of August 2015 to March 2016, for obtaining credible and consolidated data. In present study we investigated BMI, Hb and S.f level with relation to socioeconomic status in children and adults from total 2040 volunteers (girls n=991, boys n=1049). The questionnaire included education, social class, age, sex, and information about dietary habits. Blood samples were collected & assessed by ELISA method and sysmex hemoglobin auto analyzer instrument for serum ferritin and hemoglobin level. The mean value of Body Mass index, the average value of hemoglobin and serum ferritin level was observed accordingly 18.6, 12.1 g/dl, 82.8 μg/l in all samples. It was concluded that monthly income of the volunteers have significant association with Hb, BMI and Serum ferritin at the P<0.01 level. However, environmental conditions, blood loss in females during menstruation, low maternal attention, socioeconomic and dietary habits are main factors which affect the BMI, Hb and S.f level in students.
铁蛋白是一种存在于网状内皮系统中的蛋白质,它不仅在血红蛋白合成过程中作为一种中等大小的蛋白质发挥作用,还作为铁传递的储存蛋白。这项横断面研究于2015年8月至2016年3月在沙希德·贝纳齐拉巴德地区进行,以获取可靠和综合的数据。在本研究中,我们调查了2040名志愿者(女孩n = 991,男孩n = 1049)中儿童和成人的体重指数(BMI)、血红蛋白(Hb)和血清铁蛋白(S.f)水平与社会经济地位的关系。问卷包括教育程度、社会阶层、年龄、性别以及饮食习惯信息。采集血样并通过酶联免疫吸附测定(ELISA)方法和sysmex血红蛋白自动分析仪检测血清铁蛋白和血红蛋白水平。所有样本的体重指数平均值、血红蛋白平均值和血清铁蛋白水平分别为18.6、12.1 g/dl、82.8 μg/l。得出的结论是,志愿者的月收入与血红蛋白、体重指数和血清铁蛋白在P<0.01水平上有显著关联。然而,环境条件、女性月经期间的失血、母亲关注度低、社会经济状况和饮食习惯是影响学生体重指数、血红蛋白和血清铁蛋白水平的主要因素。