Fritel Xavier, Ringa Virginie, Varnoux Noëlle, Fauconnier Arnaud, Piault Stéphanie, Bréart Gérard
INSERM Unité 149 (Unité de Recherches Epidémiologiques en Santé Périnatale et Santé des Femmes), Villejuif Cedex, France.
BJOG. 2005 Dec;112(12):1646-51. doi: 10.1111/j.1471-0528.2005.00763.x.
To estimate the prevalence of severe stress urinary incontinence (SUI) among perimenopausal women and to examine potential obstetric risk factors.
Mail survey of female volunteers for epidemiological research.
Postal questionnaire on SUI.
Three thousand one hundred and fourteen women aged 49-61 years who comprised the GAZEL cohort.
Logistic regression using data from the entire cohort to estimate the impact of risk factors. A second logistic regression using data from women who had given birth included obstetric history.
Prevalence of severe SUI defined by the response 'often' or 'all the time' to the question 'Does urine leak when you are physically active, cough or sneeze?'
Two thousand six hundred and twenty-five women (85%) completed and returned the questionnaire The frequency of SUI reported in the preceding four weeks was as follows: 'never' 32%, 'occasionally' 28%, 'sometimes' 26%, 'often' 10% and 'all the time' 5%. Prevalence of severe SUI was lowest among nulliparous women (7%), but it was similar among parous women regardless of birth number (14-17%). The prevalence of severe SUI was not associated with mode of delivery (14% for women delivered by caesarean only vs 16% for vaginal births). Significant risk factors for severe SUI were high body mass index (BMI >30), diabetes mellitus, previous incontinence surgery, parity and first delivery under the age of 22 years.
Previous pregnancy itself is a risk factor for severe SUI among women who reach the age of 50. In this age group the impact of the mode of delivery (spontaneous, forceps or caesarean) on severe SUI is slight.
评估围绝经期女性中重度压力性尿失禁(SUI)的患病率,并探讨潜在的产科危险因素。
对女性志愿者进行邮件调查以开展流行病学研究。
关于SUI的邮政问卷调查。
3114名年龄在49 - 61岁之间的女性,她们构成了GAZEL队列。
使用整个队列的数据进行逻辑回归,以评估危险因素的影响。对有生育史的女性数据进行第二次逻辑回归,纳入产科病史。
对“您在进行体育活动、咳嗽或打喷嚏时会漏尿吗?”这个问题回答“经常”或“一直”所定义的重度SUI患病率。
2625名女性(85%)完成并返还了问卷。前四周报告的SUI频率如下:“从不”32%,“偶尔”28%,“有时”26%,“经常”10%,“一直”5%。重度SUI患病率在未生育女性中最低(7%),但在已生育女性中,无论生育次数多少,患病率相似(14 - 17%)。重度SUI患病率与分娩方式无关(仅剖宫产分娩的女性为14%,阴道分娩的女性为16%)。重度SUI的显著危险因素包括高体重指数(BMI>30)、糖尿病、既往失禁手术史、生育情况以及首次分娩年龄在22岁以下。
既往怀孕本身是50岁及以上女性发生重度SUI的一个危险因素。在这个年龄组中,分娩方式(自然分娩、产钳助产或剖宫产)对重度SUI的影响较小。