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儿科急诊科的过敏反应:与成人的不同模式。

Paediatric emergency department anaphylaxis: different patterns from adults.

作者信息

Braganza S C, Acworth J P, Mckinnon D R L, Peake J E, Brown A F T

机构信息

Department of Emergency Medicine, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia.

出版信息

Arch Dis Child. 2006 Feb;91(2):159-63. doi: 10.1136/adc.2004.069914. Epub 2005 Nov 24.

Abstract

BACKGROUND AND AIMS

Data on acute paediatric anaphylaxis presentations to the emergency department (ED) are limited. All allergic presentations to one Australian paediatric ED were studied to determine epidemiological, clinical, and outcome data.

METHODS

Retrospective, case based study of patients under 16 years attending one metropolitan, paediatric teaching hospital ED in Australia over three years. The medical records of patients presenting with generalised allergic reactions and anaphylaxis satisfying relevant ICD-9-CM diagnostic codes were studied. The incidence, age, sex ratio, co-morbidities, likely aetiology, clinical features, management, and disposal were determined.

RESULTS

A total of 526 children with generalised allergic reactions, and 57 with anaphylaxis were included in the study. This represented incidences of 9.3:1000 ED presentations for generalised allergic reactions and 1:1000 for anaphylaxis. There were no fatalities. In anaphylaxis cases, a cause was recognised in 68.4%. Cutaneous features were present in 82.5%. A past history of asthma was reported in 36.8%. Adrenaline was used in 39.3% of severe anaphylaxis cases. The ED alone definitively cared for 97.8% of all patients. Follow up was inadequate in cases of anaphylaxis.

CONCLUSIONS

This is the first reported incidence figure for paediatric anaphylaxis ED presentations in Australia, and is less than that reported in adults in the same local population. However, the incidence of generalised allergic reactions of 9.3:1000 was greater than in the adults. Virtually all paediatric allergic cases may be managed in the ED alone, provided that the importance of specialist follow up, particularly for severe anaphylaxis, is recognised.

摘要

背景与目的

关于儿科急性过敏反应在急诊科就诊情况的数据有限。本研究对一家澳大利亚儿科急诊科的所有过敏就诊病例进行了分析,以确定其流行病学、临床特征及转归数据。

方法

对澳大利亚一家大都市儿科教学医院急诊科3年内16岁以下患者进行回顾性、病例对照研究。研究符合相关国际疾病分类第九版临床修订本(ICD - 9 - CM)诊断编码的全身性过敏反应和过敏反应患者的病历。确定发病率、年龄、性别比、合并症、可能病因、临床特征、治疗及处置情况。

结果

本研究共纳入526例全身性过敏反应儿童及57例过敏反应患儿。全身性过敏反应的发病率为每1000次急诊就诊9.3例,过敏反应为每1000次急诊就诊1例。无死亡病例。在过敏反应病例中,68.4%可明确病因。82.5%出现皮肤症状。36.8%有哮喘既往史。39.3%的严重过敏反应病例使用了肾上腺素。仅急诊科就确诊治疗了所有患者的97.8%。过敏反应病例的随访不足。

结论

这是澳大利亚首次报道的儿科过敏反应在急诊科就诊的发病率数据,低于同一地区成人报道的数据。然而,全身性过敏反应每1000次急诊就诊9.3例的发病率高于成人。只要认识到专科随访的重要性,尤其是对于严重过敏反应,几乎所有儿科过敏病例均可仅在急诊科进行处理。

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