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[十年期多氯联苯指南——平衡卫生学与医学/环境毒理学观点的尝试]

[10-year PCB Guideline--attempt to balance hygienic and medical/environmental-toxicological views].

作者信息

Ewers U, Rosskamp E, Heudorf U, Mergner H-J

机构信息

Hygiene-Institut des Ruhrgebiets, Gelsenkirchen.

出版信息

Gesundheitswesen. 2005 Nov;67(11):809-19. doi: 10.1055/s-2005-858784.

Abstract

PURPOSE

In 1995 a guideline was established in Germany, which requires the remediation of buildings with elevated indoor air concentrations of polychlorinated biphenyls (PCB). The action limit is 3000 ng/m(3). The tolerable PCB indoor air concentration is 300 ng/m(3). The aim of remediation actions is to reduce PCB in indoor air to levels < 300 ng/m(3) by removing the sources of PCB in buildings (mainly sealants, ceiling plates, wall colours). Based on this guideline a great number of school buildings, university buildings and administration buildings constructed in the 1960-ties and 1970-ties were renovated. In this paper, the toxicological basis of the aforementioned guide values are discussed. Furthermore, recent papers and proposals to establish lower guideline values for PCB in indoor air are discussed.

CONCLUSIONS

The existing PCB guideline should be revised. When revising the guide values for PCB in indoor air it should be kept in mind that human PCB exposure is mainly via food, that PCB intake via food has been declining since more than 20 years, and that there is only a minor increase of PCB blood levels following inhalation of PCB in indoor air. In public discussions it should be clearly stated that remediation of PCB contaminated buildings is a preventive action. PCB concentrations in indoor air, which are associated with significant health risks, are presumably much higher than the current action value.

摘要

目的

1995年德国制定了一项准则,要求对室内空气中多氯联苯(PCB)浓度升高的建筑物进行修复。行动限值为3000纳克/立方米。室内空气中PCB的可耐受浓度为300纳克/立方米。修复行动的目的是通过清除建筑物中的PCB来源(主要是密封剂、天花板板材、墙面涂料),将室内空气中的PCB浓度降低至<300纳克/立方米。基于该准则,大量建于20世纪60年代和70年代的学校建筑、大学建筑和行政建筑进行了翻新。本文讨论了上述指导值的毒理学依据。此外,还讨论了近期关于为室内空气中的PCB制定更低指导值的论文和提议。

结论

现有的PCB准则应予以修订。在修订室内空气中PCB的指导值时,应牢记人类接触PCB主要通过食物,自20多年来通过食物摄入的PCB一直在下降,并且吸入室内空气中的PCB后血液中PCB水平仅略有升高。在公众讨论中应明确指出,对受PCB污染建筑物的修复是一项预防措施。与重大健康风险相关的室内空气中PCB浓度可能远高于当前的行动值。

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