Call Mindy K, Grogg Matthew W, Tsonis Panagiotis A
University of Dayton, Ohio 45469, USA.
Anat Rec B New Anat. 2005 Nov;287(1):42-8. doi: 10.1002/ar.b.20084.
Lens regeneration in newts is a remarkable process, whereby a lost tissue is replaced by transdifferentiation of adult tissues that only a few organisms possess. In this review, we will touch on the approaches being used to study this phenomenon, recent advances in the field of lens regeneration, similarities and differences between development and regeneration, as well as the potential role stem cells may play in understanding this process.
蝾螈的晶状体再生是一个非凡的过程,在此过程中,丢失的组织通过成体组织的转分化得以替换,而只有少数生物具备这种能力。在这篇综述中,我们将探讨用于研究这一现象的方法、晶状体再生领域的最新进展、发育与再生之间的异同,以及干细胞在理解这一过程中可能发挥的潜在作用。