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[非侵袭性腺癌中胃黏膜发育异常评估的显微分光光度测定标准]

[The microspectrophotometric criteria in estimating gastric mucosa dysplasia in non-invasive adenocarcinoma].

作者信息

Avdalian A M, Klimachev V V, Lazarëv A F

出版信息

Vopr Onkol. 2005;51(4):450-4.

Abstract

Computer analysis was carried out of images of changes in area and ploidy of gastric mucous nuclei associated with concomitant pathology, dysplasia and non-invasive adenocarcinoma of the stomach. In grave dysplasia, the area and ploidy of a nucleus were 213.7 +/- 3.42 microm2 and 10.2 +/- 0.2 c, and in well- or moderately differentiated cell adenocarcinoma--333.8 +/- 16.5 microm2 and 14.95 +/- 1.9 c, respectively. It is suggested that this evidence can contribute to a more accurate estimating of pathological processes taking place in the gastric mucosa when differential diagnosis between dysplasia and stomach cancer is undertaken.

摘要

对与胃部伴随病变、发育异常及非侵袭性腺癌相关的胃黏膜细胞核面积和倍性变化的图像进行了计算机分析。在严重发育异常中,细胞核的面积和倍性分别为213.7±3.42平方微米和10.2±0.2c,在高分化或中分化细胞腺癌中分别为333.8±16.5平方微米和14.95±1.9c。建议该证据有助于在对发育异常和胃癌进行鉴别诊断时更准确地评估胃黏膜中发生的病理过程。

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