Speroni Karen Gabel, Dawson Elaine, Atherton Martin, Corriher Joy
Inova Loudoun Hospital, Leesburg, VA, USA.
AAOHN J. 2005 Nov;53(11):477-83.
A convenience sample of hospital workers, those receiving influenza vaccine and those not receiving vaccine, were asked to complete questionnaires delineating the occurrence of symptoms (e.g., fever, headache, extreme tiredness, dry cough, sore throat, runny nose, stuffy nose, muscle aches) and absenteeism in the 7-day period post-vaccination if vaccinated. Those unvaccinated completed the questionnaire in a self-selected 7 consecutive day period during the study conducted from November 2004 to February 2005. Those receiving either Fluzone or FluMist reported significantly fewer symptoms and related absenteeism than the unvaccinated group (p < .05). Administration of influenza vaccine did not result in higher rates of post-vaccination symptoms as compared to an unvaccinated group. Further, vaccinated employees did not experience higher absenteeism rates as a result of receiving either influenza vaccine. However, for those reporting absenteeism as a result of symptoms, mean absenteeism days were highest in the FluMist group (4.5 days) compared to the unvaccinated group (2.1 days) and the Fluzone group (1.9 days).
我们选取了一个便利样本,包括医院工作人员,其中有接种流感疫苗的和未接种疫苗的,要求他们填写问卷,描述接种疫苗后7天内出现症状(如发烧、头痛、极度疲劳、干咳、喉咙痛、流鼻涕、鼻塞、肌肉疼痛)的情况以及缺勤情况(如果接种了疫苗)。未接种疫苗的人员在2004年11月至2005年2月进行的研究期间自行选择连续7天填写问卷。与未接种疫苗的组相比,接种Fluzone或FluMist的人员报告的症状和相关缺勤情况明显更少(p < 0.05)。与未接种疫苗的组相比,接种流感疫苗并未导致接种后症状发生率更高。此外,接种疫苗的员工也不会因为接种任何一种流感疫苗而出现更高的缺勤率。然而,对于那些因症状而缺勤的人来说,FluMist组的平均缺勤天数最高(4.5天),相比之下,未接种疫苗的组为(2.1天),Fluzone组为(1.9天)。