Tanimura S, Arita K, Iwao F, Kasai M, Fujita Y, Kawasaki H, Abe R, Sawamura D, Kimura T, Shimizu H
Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
Clin Exp Dermatol. 2006 Jan;31(1):68-70. doi: 10.1111/j.1365-2230.2005.01974.x.
Folliculosebaceous cystic hamartoma (FSCH) is a rare cutaneous hamartoma composed of dilated folliculosebaceous units associated with mesenchymal elements. Two cases of FSCH with typical histopathological features are reported. Patient 1 was a 60-year-old man presented with a normal skin-coloured asymptomatic nodule on his scalp. Patient 2 was a 70-year-old man with an asymptomatic nodule on his right auricle that had persisted for the previous 15 years. In all, 34 cases of FSCH have been reported in the English literature. Clinically, the lesions are asymptomatic, usually rubbery to firm in consistency, and usually occur on or above the neck (> 90%). Most lesions do not exceed 25 mm in diameter (> 90%). Histopathologically, FSCH shares several similar features to sebaceous trichofolliculoma, but it is usually possible to differentiate these two tumours.
毛囊皮脂腺囊性错构瘤(FSCH)是一种罕见的皮肤错构瘤,由扩张的毛囊皮脂腺单位与间充质成分组成。报告了2例具有典型组织病理学特征的FSCH。病例1为一名60岁男性,头皮出现一个肤色正常、无症状的结节。病例2为一名70岁男性,右耳廓有一个无症状结节,已持续15年。英文文献中总共报道了34例FSCH。临床上,这些病变无症状,质地通常为橡胶样至坚硬,通常发生在颈部或颈部以上(>90%)。大多数病变直径不超过25 mm(>90%)。组织病理学上,FSCH与皮脂腺毛囊瘤有一些相似特征,但通常可以区分这两种肿瘤。