Koreeda Nobuko, Iwano Yoshihiro, Kishida Mamoru, Otsuka Ayako, Kawamoto Aki, Sugano Naoyuki, Ito Koichi
Department of Periodontology, Nihon University School of Dentistry, Tokyo, Japan.
J Oral Sci. 2005 Sep;47(3):159-64. doi: 10.2334/josnusd.47.159.
Sex hormones are believed to be a risk factor for periodontitis because of their ability to proliferate specific periodontal microorganisms and affect host immunologic response. In this case report, gingival redness and swelling occurred during the menstrual cycle, although the patient maintained good oral hygiene during periodontal treatment. Medical history revealed that exacerbation of gingival inflammation corresponded to the menstrual cycle and occurred during the ovulation period, when estrogen levels are high. Mean bleeding index of the ovulation period (18.9%) showed higher levels than that during the menstrual phase (5.3%). This case indicates that frequent and effective maintenance should be provided while considering the influence of the menstrual cycle, as sex hormones may be involved in exacerbating gingival inflammation.
性激素被认为是牙周炎的一个风险因素，因为它们能够使特定的牙周微生物增殖并影响宿主免疫反应。在本病例报告中，尽管患者在牙周治疗期间保持了良好的口腔卫生，但在月经周期中仍出现了牙龈红肿。病史显示，牙龈炎症的加重与月经周期相对应，且发生在雌激素水平较高的排卵期。排卵期的平均出血指数（18.9%）高于月经期（5.3%）。本病例表明，由于性激素可能参与加剧牙龈炎症，在考虑月经周期影响的同时，应提供频繁且有效的维护措施。
