Bray Clifford M, West Christopher E
Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, UK.
New Phytol. 2005 Dec;168(3):511-28. doi: 10.1111/j.1469-8137.2005.01548.x.
As obligate phototrophs, plants harness energy from sunlight to split water, producing oxygen and reducing power. This lifestyle exposes plants to particularly high levels of genotoxic stress that threatens genomic integrity, leading to mutation, developmental arrest and cell death. Plants, which with algae are the only photosynthetic eukaryotes, have evolved very effective pathways for DNA damage signalling and repair, and this review summarises our current understanding of these processes in the responses of plants to genotoxic stress. We also identify how the use of new and emerging technologies can complement established physiological and ecological studies to progress the application of this knowledge in biotechnology.
作为专性光合生物，植物利用阳光中的能量分解水，产生氧气并生成还原力。这种生活方式使植物面临特别高水平的基因毒性应激，这种应激会威胁基因组完整性，导致突变、发育停滞和细胞死亡。植物与藻类是仅有的光合真核生物，它们进化出了非常有效的DNA损伤信号传导和修复途径，本综述总结了我们目前对植物在基因毒性应激反应中这些过程的理解。我们还确定了如何利用新兴技术补充已有的生理学和生态学研究，以推动这些知识在生物技术中的应用。
