Department of Molecular Biology and Genetics, Laboratory of Regulation of Gene Expression, Institute of Plant Physiology and Genetics, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.
Int J Mol Sci. 2023 Mar 7;24(6):5105. doi: 10.3390/ijms24065105.
The purpose of this review is to critically evaluate the effects of different stress factors on higher plants, with particular attention given to the typical and unique dose-dependent responses that are essential for plant growth and development. Specifically, this review highlights the impact of stress on genome instability, including DNA damage and the molecular, physiological, and biochemical mechanisms that generate these effects. We provide an overview of the current understanding of predictable and unique dose-dependent trends in plant survival when exposed to low or high doses of stress. Understanding both the negative and positive impacts of stress responses, including genome instability, can provide insights into how plants react to different levels of stress, yielding more accurate predictions of their behavior in the natural environment. Applying the acquired knowledge can lead to improved crop productivity and potential development of more resilient plant varieties, ensuring a sustainable food source for the rapidly growing global population.
本文旨在批判性地评估不同应激因素对高等植物的影响,特别关注对植物生长和发育至关重要的典型和独特的剂量依赖性反应。具体而言,本文重点介绍了应激对基因组不稳定性的影响,包括 DNA 损伤以及产生这些效应的分子、生理和生化机制。我们概述了目前对植物在暴露于低剂量或高剂量应激时生存的可预测和独特的剂量依赖性趋势的理解。了解应激反应(包括基因组不稳定性)的正反两方面影响,可以深入了解植物对不同水平应激的反应方式,从而更准确地预测它们在自然环境中的行为。应用所获得的知识可以提高作物的生产力,并有可能开发出更具弹性的植物品种,为快速增长的全球人口提供可持续的食物来源。