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[不同穴位电针对单眼视神经离断家兔闪光视觉诱发电位的影响]

[Effects of electroacupuncture at different acupoints on FVEP in the rabbit with separated monocular optic nerve].

作者信息

Zhou Hua-Xiang, Liu Wen-Zhou, Duan Jun-Guo, Jiang Wen-Shan, Chen Xiao-Li

机构信息

Laboratory of Ophthalmology, Chengdu University of TCM, Sichuan 610075, China.

出版信息

Zhongguo Zhen Jiu. 2005 Oct;25(10):725-8.

PMID:16318136
Abstract

OBJECTIVE

To study the effect of acupuncture and moxibustion on the visual system and the mechanism.

METHODS

Twenty-four rabbits were randomly divided into a "Hegu" (Ll 4) group and a "Taixi" (KI 3) group, 12 rabbits in each group. The rabbit model with separated monocular optic nerve was developed, cutting the link between the retina with the center, but do not injure the blood circulation in the retina. The effect of electroacupuncture on flicker vision evoked potential (FVEP) was investigated.

RESULTS

When the optic nerve was cut off, the distal fibers of descending regulating the retina were cut off, the FVEP of the operative eye extinguished. Elctroacupuncture at "Hegu" (LI 4) and "Taixi" (KI 3) at various stages have stronger inhibiting action on the latent time and amplitudes of N1, P1, N2 of FVEP, marked by prolongation of the latent time of peak, and obvious decrease of the amplitude. And this inhibiting action has difference of acupoints.

CONCLUSION

The distal fiber plays a certain role in the process of electroacupuncture influencing flicker electroretinogram (FERG) and FVEP, but the effect of acupuncture on FERG is induced through the distal fibers to influence the retina in a limited extent, but not through the central descending inhibition.

摘要

目的

研究针灸对视觉系统的作用及其机制。

方法

将24只家兔随机分为“合谷”(LI 4)组和“太溪”(KI 3)组,每组12只。制备家兔单眼视神经离断模型,切断视网膜与中枢的联系,但不损伤视网膜血液循环。观察电针对闪光视觉诱发电位(FVEP)的影响。

结果

切断视神经后,下行调节视网膜的远心端纤维被切断,手术眼FVEP消失。不同时段针刺“合谷”(LI 4)、“太溪”(KI 3)对FVEP的N1、P1、N2潜伏期和波幅有较强抑制作用,表现为峰潜伏期延长,波幅明显降低,且穴位之间存在这种抑制作用的差异。

结论

远心端纤维在电针影响闪光视网膜电图(FERG)和FVEP过程中起一定作用,但针刺对FERG的影响是通过远心端纤维在一定程度上影响视网膜,而非通过中枢下行抑制。

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