Wu Zi-jian, Cai Rong-lin, Long Di-he, He Lu, Hu Ling
Research Center for Acu-moxibustion and Meridian-collaterals, Anhui College of Chinese Medicine, Hefei 230038, China.
Zhen Ci Yan Jiu. 2010 Feb;35(1):32-6.
To observe the effect of electroacupuncture (EA) of different acupoints on activities of the cardiac sympathetic nerve in rabbits with acute myocardial schemia (AMI).
A total of 40 Chinchilla rabbits were randomized into normal control, model, Shenmen (HT 7), Taixi (KI 3) and non-acupoint groups (n8/group). AMI model was established by intravenous injection of pituitrin (3 U/kg). EA (1.1 mA, 2 Hz) was applied to bilateral HT 7, KI 3 and non-acupoint (the bulge site of the triangular muscle) for 10 mm. The rabbit's cardiac sympathetic discharges were recorded by BIOPAC under anesthesia.
In comparison with control group, the heart rate (HR) and the frequency of cardiac sympathetic discharges (CSD) decreased significantly after AMI (P < 0.01). At the moment of cease of EA, at 20 mm after EA, HR and 050 frequency in HT 7 group were significantly higher than those of model group (P < 0.01), suggesting a favorable inhibition of EA of HT 7 on the decreased HR and OSO. No significant differences were found between KI 3 and model groups, and between KI 3 and non-acupoint groups in both HR and OSD at any time courses (P > 0.05).
EA of HT 7 can correct AMI-induced decrease of both HR and OSO in the rabbit, while EA of KI 3 and non-acupoint have not this effect, suggesting a relatively specific efficacy of EA of different acupoints on cardiac sympathetic activities.
观察电针不同穴位对急性心肌缺血（AMI）家兔心脏交感神经活动的影响。
将40只青紫蓝兔随机分为正常对照组、模型组、神门（HT 7）组、太溪（KI 3）组和非穴位组（每组8只）。通过静脉注射垂体后叶素（3 U/kg）建立AMI模型。将电针（1.1 mA，2 Hz）分别作用于双侧HT 7、KI 3和非穴位（三角肌隆起处）10分钟。在麻醉状态下用BIOPAC记录家兔心脏交感神经放电情况。
与对照组相比，AMI后心率（HR）和心脏交感神经放电频率（CSD）显著降低（P<0.01）。电针停止时、电针后20分钟，HT 7组的HR和050频率显著高于模型组（P<0.01），提示HT 7电针对HR和OSO降低有良好的抑制作用。在任何时间点，KI 3组与模型组之间以及KI 3组与非穴位组之间的HR和OSD均无显著差异（P>0.05）。
HT 7电针可纠正AMI所致家兔HR和OSO的降低，而KI 3电针和非穴位电针无此作用，提示不同穴位电针在心脏交感神经活动方面具有相对特异的效应。
