Boralevi Franck, Marco-Bonnet Josefina, Lepreux Sebastien, Buzenet Christel, Couprie Bernard, Taïeb Alain
Department of Dermatology, Hôpital Saint-André, Bordeaux, France.
Dermatology. 2006;212(1):36-40. doi: 10.1159/000089020.
Pityriasis versicolor (tinea versicolor) is a common skin disorder due to Malassezia usually affecting adolescents and young adults, more frequently in the tropics. Facial involvement, isolated or not, is not frequent in white adults.
Here, we report a possible atypical hyperkeratotic form of dermatosis of the face, in two young immunocompetent Caucasian patients, particularly recalcitrant to therapy.
Skin scrapings grew yeasts belonging to the genus Malassezia, including both M. globosa and M. sympodialis. This unusual variant needs long-term therapy with systemic and topical imidazoles together with facial cleansing.
We propose the name hyperkeratotic head and neck Malassezia dermatosis for this distinctive clinical entity. This variant of pityriasis versicolor should be considered in the differential diagnosis of seborrheic dermatitis and dermatitis neglecta.
花斑糠疹（又称花斑癣）是一种常见的皮肤疾病，由马拉色菌引起，通常影响青少年和年轻人，在热带地区更为常见。面部受累，无论是否孤立出现，在白人成年人中并不常见。
在此，我们报告两例免疫功能正常的年轻白种人患者可能出现的一种非典型角化过度型面部皮肤病，对治疗特别顽固。
皮肤刮屑培养出属于马拉色菌属的酵母菌，包括球形马拉色菌和合轴马拉色菌。这种不寻常的变体需要全身和局部使用咪唑类药物进行长期治疗，并配合面部清洁。
我们为此独特的临床实体提出“角化过度型头颈部马拉色菌皮肤病”这一名称。在脂溢性皮炎和忽视性皮炎的鉴别诊断中应考虑这种花斑糠疹变体。
