Sozen Ibrahim, Small Laurie, Kowalski Mark, Mayo Sara W, Hurwitz Craig A
Department of Obstetrics and Gynecology, Penobscot Valley Hospital, Lincoln, ME 04457, USA.
J Reprod Med. 2005 Oct;50(10):793-5.
Carcinoma metastatic to the uterine cervix is very rare. The most frequent nongenital primary sites are the stomach and colon.
A 17-year-old woman presented to the office for an annual gynecologic examination. The Pap smear and cervical biopsy of a 1.5-cm lesion were positive for adenocarcinoma. Subsequent surgery revealed a sigmoid tumor with extensive abdominal and pelvic carcinomatosis. Following 2 cycles of ineffective chemotherapy, the patient died 4 months after her initial visit to the gynecologist.
To our knowledge, this was the youngest patient in the literature with colon cancer metastatic to the cervix. This case focuses attention on the diagnostic challenge posed by an incidental finding of a cervical adenocarcinoma in the presence of an asymptomatic primary tumor.
转移至子宫颈的癌非常罕见。最常见的非生殖系统原发部位是胃和结肠。
一名17岁女性到诊所进行年度妇科检查。对一个1.5厘米病变进行的巴氏涂片检查和宫颈活检显示腺癌呈阳性。后续手术发现乙状结肠肿瘤伴广泛的腹部和盆腔癌转移。在进行了2个周期无效的化疗后,该患者在初次就诊于妇科医生4个月后死亡。
据我们所知,这是文献中最年轻的结肠癌转移至子宫颈的患者。该病例使人们关注在存在无症状原发肿瘤的情况下偶然发现宫颈腺癌所带来的诊断挑战。