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[华法林中断后冠状动脉扩张导致血栓性冠状动脉闭塞:一例报告]

[Coronary ectasia resulting in thrombotic coronary occlusion after warfarin interruption: a case report].

作者信息

Fukuhara Shinya, Takase Eiji, Fujimoto Takatomi, Takami Yasuhiro, Yamamoto Kazuo, Nishida Taku, Morimoto Atsushi

机构信息

Division of Cardiology, Saiseikai-Suita Hospital, Osaka.

出版信息

J Cardiol. 2005 Nov;46(5):195-200.

Abstract

A 68-year-old man taking aspirin and warfarin for ectatic right coronary artery complained of chest pain and was admitted to our hospital with acute myocardial infarction. He had discontinued taking warfarin due to nail bleeding for a month. Coronary angiography revealed total occlusion at segment 3 of the ectatic right coronary artery with massive thrombus. Because of unsuccessful reperfusion by an aspiration device, a 5F straight catheter was inserted into the ectatic right coronary artery to aspirate the massive thrombus, and Thrombolysis in Myocardial Infarction grade 3 flow reperfusion was obtained. Intravascular ultrasonography showed "moyamoya" vessels in the ectatic right coronary artery, suggesting an abnormal coronary flow pattern, but there was no evidence of unstable plaque. Warfarization should be considered to treat ectatic coronary artery.

摘要

一名68岁男性因右冠状动脉扩张服用阿司匹林和华法林,主诉胸痛,因急性心肌梗死入院。他因指甲出血已停用华法林1个月。冠状动脉造影显示扩张的右冠状动脉第3段完全闭塞并伴有大量血栓。由于抽吸装置再灌注未成功,将一根5F直导管插入扩张的右冠状动脉以抽吸大量血栓,获得了心肌梗死溶栓3级血流再灌注。血管内超声显示扩张的右冠状动脉中有“烟雾病样”血管,提示冠状动脉血流模式异常,但无不稳定斑块证据。应考虑使用华法林治疗扩张型冠状动脉。

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