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早期胆管损伤的专科修复

Early specialist repair of biliary injury.

作者信息

Thomson B N J, Parks R W, Madhavan K K, Wigmore S J, Garden O J

机构信息

Department of Clinical and Surgical Sciences (Surgery), Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK.

出版信息

Br J Surg. 2006 Feb;93(2):216-20. doi: 10.1002/bjs.5194.

Abstract

BACKGROUND

Considerable debate surrounds the timing of repair of injury to the common bile duct following cholecystectomy. In the absence of sepsis or significant peritoneal soiling, repair within the first week may be optimal. This study compared the outcome of early (within the first 2 weeks) and delayed (between 2 weeks and 6 months) repair.

METHODS

Data on all patients referred with biliary injuries were recorded prospectively. In the absence of sepsis or significant peritoneal soiling, repair was considered within 2 weeks.

RESULTS

Between November 1988 and November 2003, 123 patients were referred with injury to the biliary tree. Repair of the injury had been attempted in 55 patients (44.7 per cent) before referral. Of the 68 patients with no previous repair, nine were managed without surgery and 59 required subsequent surgical reconstruction of the ductal injury. Within the first 2 weeks after injury, 22 patients underwent primary biliary repair and three had revision of a failed biliary repair. Between 2 weeks and 6 months, a further 22 injuries were repaired. Successful repair was possible in 22 of 25 early repairs compared with 20 of 22 delayed repairs (P = 0.615). The overall operative mortality rate for patients undergoing repair was 4 per cent (two of 47 patients).

CONCLUSION

A successful outcome was achieved in a high proportion of patients (42 of 47) when repair of the bile duct injury was undertaken in a unit experienced in the management of biliary injury. In selected patients, early repair within the first 2 weeks resulted in a similar outcome to that of delayed repair.

摘要

背景

胆囊切除术后胆总管损伤的修复时机存在诸多争议。在没有脓毒症或严重腹腔污染的情况下,伤后第一周内进行修复可能是最佳选择。本研究比较了早期(伤后2周内)和延迟(2周与6个月之间)修复的效果。

方法

前瞻性记录所有因胆管损伤转诊患者的数据。在没有脓毒症或严重腹腔污染的情况下,考虑在2周内进行修复。

结果

1988年11月至2003年11月期间,123例患者因胆管树损伤前来就诊。55例患者(44.7%)在转诊前已尝试进行损伤修复。在68例此前未行修复的患者中,9例非手术治疗,59例随后需要进行胆管损伤的手术重建。伤后2周内,22例患者接受了一期胆管修复,3例对失败的胆管修复进行了翻修。在2周与6个月之间,又有22例损伤得到修复。25例早期修复中有22例成功修复,而22例延迟修复中有20例成功修复(P = 0.615)。接受修复患者的总体手术死亡率为4%(47例患者中有2例)。

结论

在一个有胆管损伤处理经验的科室对胆管损伤进行修复时,大部分患者(47例中的42例)取得了成功的结果。在部分患者中,伤后2周内的早期修复与延迟修复效果相似。

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