Czerniak A, Thompson J N, Soreide O, Benjamin I S, Blumgart L H
Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London.
Surg Gynecol Obstet. 1988 Jul;167(1):33-8.
Twelve of 123 patients who were treated for benign stricture of the bile duct after cholecystectomy presented with an external fistula of the biliary tract. Nine of these patients had undergone multiple operations prior to referral, six having undergone earlier attempts at repair of the bile duct. Two patients initially required urgent laparotomy for drainage of infected abdominal collections. Distal obstruction of the bile duct below the origin of the fistula was present in five patients. Repair of the bile duct was undertaken after careful investigation and correction of nutritional, fluid and electrolyte status in five patients who had little prospect of spontaneous closure of the fistula. The other seven patients were initially treated conservatively; in three, the fistula closed at five to nine weeks without complication, and no further surgical treatment has been required (a range of six to 36 months). The remaining four patients required delayed operation after the development of cholangitis or jaundice. The overall median survival time between development of fistula and operative repair was 3.5 months, and all nine of these patients remained asymptomatic with normal results from liver function tests (a median follow-up period of 17 months). The need for careful initial assessment prior to repair of the bile duct and the possibility of conservative treatment for patients with a postcholecystectomy fistula of the biliary tract are emphasized.
123例胆囊切除术后因良性胆管狭窄接受治疗的患者中,有12例出现了胆道外瘘。这些患者中有9例在转诊前接受了多次手术,其中6例曾早期尝试修复胆管。2例患者最初需要紧急剖腹手术以引流感染的腹腔积液。5例患者在瘘管起源以下存在胆管远端梗阻。对于瘘管几乎没有自行闭合可能的5例患者,在仔细评估并纠正营养、液体和电解质状况后进行了胆管修复。其他7例患者最初接受保守治疗;其中3例在5至9周时瘘管闭合且无并发症,无需进一步手术治疗(随访时间为6至36个月)。其余4例患者在发生胆管炎或黄疸后需要延迟手术。瘘管形成至手术修复之间的总体中位生存时间为3.5个月,所有9例患者均无症状,肝功能检查结果正常(中位随访期为17个月)。强调了在修复胆管之前进行仔细的初始评估的必要性以及对胆囊切除术后胆道瘘患者进行保守治疗的可能性。