精神分裂症中感觉预测缺陷的证据。
Evidence for sensory prediction deficits in schizophrenia.
作者信息
Shergill Sukhwinder S, Samson Gabrielle, Bays Paul M, Frith Chris D, Wolpert Daniel M
机构信息
Institute of Neurology, University College London.
出版信息
Am J Psychiatry. 2005 Dec;162(12):2384-6. doi: 10.1176/appi.ajp.162.12.2384.
OBJECTIVE
Patients with schizophrenia experiencing delusions and hallucinations can misattribute their own actions to an external source. The authors test the hypothesis that patients with schizophrenia have defects in their ability to predict the sensory consequences of their actions.
METHOD
The authors measured sensory attenuation of self-produced stimuli by patients with schizophrenia and by healthy subjects.
RESULTS
Patients with schizophrenia demonstrated significantly less sensory attenuation than healthy subjects.
CONCLUSIONS
Patients with a diagnosis of schizophrenia have a dysfunction in their predictive mechanisms.
目的
患有妄想和幻觉的精神分裂症患者可能会将自己的行为错误地归因于外部来源。作者检验了精神分裂症患者在预测自身行为的感觉后果方面存在缺陷的假设。
方法
作者测量了精神分裂症患者和健康受试者对自身产生的刺激的感觉衰减。
结果
精神分裂症患者表现出的感觉衰减明显少于健康受试者。
结论
被诊断为精神分裂症的患者其预测机制存在功能障碍。
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