Nilsson Peter M, Nilsson Jan-Ake, Ostergren Per-Olof, Berglund Göran
Department of Medicine, University Hospital, Malmö, Sweden.
Scand J Public Health. 2005;33(6):412-23. doi: 10.1080/14034940510005905.
Adverse social factors predict increased mortality. This study aimed to assess the influence of social class and marital status on mortality, adding an adult life course perspective.
In total, 32,907 males and 20,204 females were evaluated based on census data in Malmö, Sweden. Of these subjects, 22,444 males and 10,902 females also took part in health screening. The main outcomes were all-cause and cause-specific mortality rates in subgroups based on social class and marital status, either measured once or repeatedly in adult life. Results were based on a total of 522,807 years of follow-up in men (5,761 deaths) and 239,815 in women (1,354 deaths).
Total and cardiovascular mortality were significantly higher in manual male employees with age-adjusted risk ratios (RR) of 1.7 (95% CI 1.5-1.9) and 1.6 (1.3-2.0) in skilled manual workers, and 2.0 (1.7-2.2) and 1.9 (1.6-2.3) in unskilled manual workers, compared with high-level non-manual employees. The differences remained after adjustment for baseline risk factors and prevalent cardiovascular disease, and were similar for women. Increased mortality risk was also documented for subjects who were divorced or unmarried (adjusted for social class), as well as being downward socially mobile or in a permanent low social class (manual) position.
Social class based on occupation, either measured once or repeatedly in adult life, is associated with marked differences in mortality risk in middle-aged subjects. People who remain married/cohabiting or remarry are at lower risk of early death than people who remain unmarried or divorced.
不良社会因素预示着死亡率上升。本研究旨在从成年人生命历程的角度评估社会阶层和婚姻状况对死亡率的影响。
基于瑞典马尔默的人口普查数据,共对32907名男性和20204名女性进行了评估。在这些受试者中,22444名男性和10902名女性还参加了健康筛查。主要结局是基于社会阶层和婚姻状况的亚组中的全因死亡率和特定病因死亡率,这些数据在成年期进行了一次或多次测量。结果基于男性总计522807年的随访(5761例死亡)和女性239815年的随访(1354例死亡)。
体力劳动者男性的总死亡率和心血管死亡率显著更高,熟练体力劳动者的年龄调整风险比(RR)为1.7(95%CI 1.5 - 1.9)和1.6(1.3 - 2.0),非熟练体力劳动者为2.0(1.7 - 2.2)和1.9(1.6 - 2.3),而高级非体力劳动者则较低。在对基线风险因素和心血管疾病患病率进行调整后,差异仍然存在,女性情况类似。离婚或未婚(经社会阶层调整)、社会地位向下流动或处于永久性低社会阶层(体力劳动者)的受试者的死亡风险也有所增加。
基于职业的社会阶层,无论在成年期测量一次还是多次,都与中年受试者的死亡风险存在显著差异有关。保持已婚/同居或再婚的人比未婚或离婚的人早死风险更低。