• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
HSP60 expression during carcinogenesis: a molecular "proteus" of carcinogenesis?致癌过程中的热休克蛋白60表达:致癌作用的分子“变形杆菌”?
Cell Stress Chaperones. 2005 Winter;10(4):263-4. doi: 10.1379/1466-1268(2005)10[263:hedcam]2.0.co;2.
2
HSP60 as a drug target.热休克蛋白 60 作为药物靶点。
Curr Pharm Des. 2013;19(3):441-51.
3
Hsp60 expression, new locations, functions and perspectives for cancer diagnosis and therapy.热休克蛋白60的表达、新定位、功能以及癌症诊断与治疗的前景
Cancer Biol Ther. 2008 Jun;7(6):801-9. doi: 10.4161/cbt.7.6.6281. Epub 2008 May 13.
4
HSP60 expression during carcinogenesis: where is the pilot?致癌过程中的热休克蛋白60表达:导向何在?
Pathol Res Pract. 2006;202(5):401-2. doi: 10.1016/j.prp.2006.02.002. Epub 2006 Mar 24.
5
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.与正常组织和肿瘤组织相比,管状腺瘤中热休克蛋白(Hsps)的定量模式揭示了Hsp10和Hsp60在大肠癌早期诊断中的价值。
Cell Stress Chaperones. 2016 Sep;21(5):927-33. doi: 10.1007/s12192-016-0721-5. Epub 2016 Aug 4.
6
HSP60 in cancer: a promising biomarker for diagnosis and a potentially useful target for treatment.热休克蛋白 60 在癌症中的作用:一种有前途的诊断生物标志物和有潜在应用价值的治疗靶点。
J Drug Target. 2022 Jan;30(1):31-45. doi: 10.1080/1061186X.2021.1920025. Epub 2021 May 3.
7
Hsp60: molecular anatomy and role in colorectal cancer diagnosis and treatment.热休克蛋白60:分子结构及其在结直肠癌诊断与治疗中的作用
Front Biosci (Schol Ed). 2011 Jan 1;3(1):341-51. doi: 10.2741/s155.
8
60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis.60千道尔顿伴侣蛋白(热休克蛋白60)在结直肠癌发生过程中过度表达。
Eur J Histochem. 2003;47(2):105-10. doi: 10.4081/814.
9
Is chlamydial heat shock protein 60 a risk factor for oncogenesis?衣原体热休克蛋白60是肿瘤发生的危险因素吗?
Cell Mol Life Sci. 2005 Jan;62(1):4-9. doi: 10.1007/s00018-004-4367-6.
10
Hsp60 regulation of tumor cell apoptosis.热休克蛋白60对肿瘤细胞凋亡的调控
J Biol Chem. 2008 Feb 22;283(8):5188-94. doi: 10.1074/jbc.M705904200. Epub 2007 Dec 17.

引用本文的文献

1
Role of Moonlighting Proteins in Disease: Analyzing the Contribution of Canonical and Moonlighting Functions in Disease Progression.蛋白质的双重功能在疾病中的作用:分析规范功能和双重功能在疾病进展中的贡献。
Cells. 2023 Jan 5;12(2):235. doi: 10.3390/cells12020235.
2
Bis-aryl-α,β-unsaturated ketone (ABK) chaperonin inhibitors exhibit selective cytotoxicity to colorectal cancer cells that correlates with levels of aberrant HSP60 in the cytosol.双芳基-α,β-不饱和酮(ABK)伴侣蛋白抑制剂对结直肠癌细胞表现出选择性细胞毒性,与细胞质中异常 HSP60 的水平相关。
Bioorg Med Chem. 2022 Dec 1;75:117072. doi: 10.1016/j.bmc.2022.117072. Epub 2022 Oct 30.
3
Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics.开发热休克蛋白60(Hsp60)的化学调节剂作为潜在疗法
Front Mol Biosci. 2018 Apr 20;5:35. doi: 10.3389/fmolb.2018.00035. eCollection 2018.
4
Quantitative patterns of Hsps in tubular adenoma compared with normal and tumor tissues reveal the value of Hsp10 and Hsp60 in early diagnosis of large bowel cancer.与正常组织和肿瘤组织相比,管状腺瘤中热休克蛋白(Hsps)的定量模式揭示了Hsp10和Hsp60在大肠癌早期诊断中的价值。
Cell Stress Chaperones. 2016 Sep;21(5):927-33. doi: 10.1007/s12192-016-0721-5. Epub 2016 Aug 4.
5
The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells.组蛋白去乙酰化酶抑制剂SAHA诱导人肺癌细胞中HSP60硝化及其通过外泌体囊泡的细胞外释放。
Oncotarget. 2016 May 17;7(20):28849-67. doi: 10.18632/oncotarget.6680.
6
CD1A-positive cells and HSP60 (HSPD1) levels in keratoacanthoma and squamous cell carcinoma.角化棘皮瘤和鳞状细胞癌中CD1A阳性细胞及热休克蛋白60(HSPD1)水平
Cell Stress Chaperones. 2016 Jan;21(1):131-137. doi: 10.1007/s12192-015-0646-4. Epub 2015 Oct 6.
7
The Chemical Biology of Molecular Chaperones--Implications for Modulation of Proteostasis.分子伴侣的化学生物学——对蛋白质稳态调节的启示
J Mol Biol. 2015 Sep 11;427(18):2931-47. doi: 10.1016/j.jmb.2015.05.010. Epub 2015 May 21.
8
Geldanamycin-induced osteosarcoma cell death is associated with hyperacetylation and loss of mitochondrial pool of heat shock protein 60 (hsp60).格尔德霉素诱导骨肉瘤细胞死亡与乙酰化过度和线粒体热休克蛋白 60(hsp60)池丢失有关。
PLoS One. 2013 Aug 28;8(8):e71135. doi: 10.1371/journal.pone.0071135. eCollection 2013.
9
Different immunohistochemical levels of Hsp60 and Hsp70 in a subset of brain tumors and putative role of Hsp60 in neuroepithelial tumorigenesis.在一组脑肿瘤中存在不同的 Hsp60 和 Hsp70 的免疫组化水平,以及 Hsp60 在神经上皮肿瘤发生中的可能作用。
Eur J Histochem. 2013 Jun 28;57(2):e20. doi: 10.4081/ejh.2013.e20.
10
Hyperthermia-enhanced TRAIL- and mapatumumab-induced apoptotic death is mediated through mitochondria in human colon cancer cells.热疗增强 TRAIL 和 mapatumumab 诱导的人结肠癌细胞凋亡死亡是通过线粒体介导的。
J Cell Biochem. 2012 May;113(5):1547-58. doi: 10.1002/jcb.24023.

本文引用的文献

1
Immunopositivity of heat shock protein 60 as a biomarker of bronchial carcinogenesis.热休克蛋白60作为支气管癌发生生物标志物的免疫阳性反应
Lancet Oncol. 2005 Oct;6(10):816. doi: 10.1016/S1470-2045(05)70393-4.
2
Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications.癌症中的热休克蛋白:诊断、预后、预测及治疗意义
Cell Stress Chaperones. 2005 Summer;10(2):86-103. doi: 10.1379/csc-99r.1.
3
Is chlamydial heat shock protein 60 a risk factor for oncogenesis?衣原体热休克蛋白60是肿瘤发生的危险因素吗?
Cell Mol Life Sci. 2005 Jan;62(1):4-9. doi: 10.1007/s00018-004-4367-6.
4
HSP10 selective preference for myeloid and megakaryocytic precursors in normal human bone marrow.热休克蛋白10(HSP10)对正常人骨髓中髓系和巨核细胞前体的选择性偏好。
Eur J Histochem. 2004 Jul-Sep;48(3):261-5.
5
Expression of heat-shock protein Hsp60 correlated with the apoptotic index and patient prognosis in human oesophageal squamous cell carcinoma.热休克蛋白Hsp60的表达与人类食管鳞状细胞癌的凋亡指数及患者预后相关。
Eur J Cancer. 2004 Dec;40(18):2804-11. doi: 10.1016/j.ejca.2004.08.013.
6
Heat shock proteins HSP27, HSP60, HSP70, and HSP90: expression in bladder carcinoma.热休克蛋白HSP27、HSP60、HSP70和HSP90:在膀胱癌中的表达
Cancer. 2003 Sep 1;98(5):970-7. doi: 10.1002/cncr.11594.
7
Ten kilodalton heat shock protein (HSP10) is overexpressed during carcinogenesis of large bowel and uterine exocervix.10千道尔顿热休克蛋白(HSP10)在大肠癌和子宫颈癌发生过程中过表达。
Cancer Lett. 2003 Jun 30;196(1):35-41. doi: 10.1016/s0304-3835(03)00212-x.
8
Immunohistochemical evaluation of PCNA, p53, HSP60, HSP10 and MUC-2 presence and expression in prostate carcinogenesis.前列腺癌发生过程中PCNA、p53、HSP60、HSP10和MUC-2存在及表达的免疫组织化学评估
Anticancer Res. 2003 Mar-Apr;23(2B):1325-31.
9
60KDa chaperonin (HSP60) is over-expressed during colorectal carcinogenesis.60千道尔顿伴侣蛋白(热休克蛋白60)在结直肠癌发生过程中过度表达。
Eur J Histochem. 2003;47(2):105-10. doi: 10.4081/814.
10
Expression of 60-kD heat shock protein increases during carcinogenesis in the uterine exocervix.60-kD热休克蛋白的表达在子宫颈癌发生过程中增加。
Pathobiology. 2002;70(2):83-8. doi: 10.1159/000067304.

HSP60 expression during carcinogenesis: a molecular "proteus" of carcinogenesis?

作者信息

Cappello Francesco, Zummo Giovanni

出版信息

Cell Stress Chaperones. 2005 Winter;10(4):263-4. doi: 10.1379/1466-1268(2005)10[263:hedcam]2.0.co;2.

DOI:10.1379/1466-1268(2005)10[263:hedcam]2.0.co;2
PMID:16333979
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1283870/
Abstract
摘要