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酪氨酸血症的脑部磁共振成像

Brain magnetic resonance imaging in tyrosinemia.

作者信息

Sener R N

机构信息

Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey.

出版信息

Acta Radiol. 2005 Oct;46(6):618-20. doi: 10.1080/02841850510021517.

DOI:10.1080/02841850510021517
PMID:16334844
Abstract

A 3.5-year-old girl with tyrosinemia is reported. A computed tomography scan of the abdomen revealed multiple hepatic nodules. Brain magnetic resonance imaging revealed bilateral high-signal changes confined to the globus pallidus on T2-weighted images. Globus pallidus lesions likely represented neuropathologic changes such as astocytosis, delayed myelination, and status spongiosus (myelin splitting and vacuolation).

摘要

报告了一名3.5岁患酪氨酸血症的女孩。腹部计算机断层扫描显示肝脏有多个结节。脑部磁共振成像显示在T2加权图像上双侧苍白球出现高信号改变。苍白球病变可能代表了诸如星形细胞增多、髓鞘形成延迟和海绵状状态（髓鞘分裂和空泡形成）等神经病理变化。

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