Ihara K, Hijii T, Kuromaru R, Ariyoshi M, Kira R, Fukushige J, Hara T
Department of Pediatrics, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Neuroradiology. 1999 Mar;41(3):195-8. doi: 10.1007/s002340050733.
We report two toddlers with portosystemic shunts who had symmetrical high-signal globus pallidus lesions on T1- but not T2-weighted MRI, and measurement of whole blood manganese at 2 years of age. These cases suggest that portosystemic shunts can cause elevation of blood manganese and result in manganese accumulation in the globus pallidus, causing high signal on T1-weighted images even in asymptomatic toddlers.
我们报告了两名患有门体分流的幼儿，他们在T1加权磁共振成像（MRI）上有对称性高信号的苍白球病变，但在T2加权MRI上没有，并且在2岁时测量了全血锰含量。这些病例表明，门体分流可导致血锰升高，并导致锰在苍白球中蓄积，即使在无症状的幼儿中也会在T1加权图像上产生高信号。
