van der Pal Floor, van Balken Michael R, Heesakkers John P F A, Debruyne Frans M J, Kiemeney Lambertus A L M, Bemelmans Bart L H
Department of Urology, Radboud University, Nijmegen Medical Centre, Nijmegen, the Netherlands.
BJU Int. 2006 Jan;97(1):113-6. doi: 10.1111/j.1464-410X.2006.05860.x.
To investigate the relationship between quality of life (QoL) and voiding variables in patients with lower urinary tract dysfunction treated with percutaneous tibial nerve stimulation (PTNS), as it is assumed that improvements in voiding will lead to a better QoL in such patients.
The study included 30 patients with urge urinary incontinence who were treated with PTNS; 24-h bladder diaries and QoL questionnaires (Short Form, SF-36, and incontinence-specific QoL) were completed at baseline and after PTNS.
There was a significant correlation (P < 0.05) between the number of pads used and the SF-36 domains of physical and vitality, between the number of incontinence episodes and the SF-36 domains of physical and role physical, between nocturia and the SF-36 domains of general and mental health, between the mean voided volume and the SF-36 domains of role physical and final, and between the mean voided volume and the incontinence-specific QoL score.
PTNS is useful for treating refractory urge incontinence and should at least be considered as a therapeutic alternative before resorting to aggressive surgery, as voiding and QoL variables significantly and quantifiably correlate in patients with refractory urge urinary incontinence who are treated with PTNS. Patients must have a reduction of >or = two pads/day before their QoL improves, and this might be the best definition of successful therapy for patients with urge urinary incontinence.
探讨经皮胫神经刺激（PTNS）治疗下尿路功能障碍患者的生活质量（QoL）与排尿变量之间的关系，因为据推测排尿改善将使此类患者的生活质量得到提高。
该研究纳入了30例接受PTNS治疗的急迫性尿失禁患者；在基线期和PTNS治疗后完成24小时膀胱日记和生活质量问卷（简表，SF - 36，以及特定于尿失禁的生活质量问卷）。
使用尿垫数量与SF - 36身体和活力领域、尿失禁发作次数与SF - 36身体和身体角色领域、夜尿症与SF - 36总体健康和心理健康领域、平均排尿量与SF - 36身体角色和最终领域以及平均排尿量与特定于尿失禁的生活质量评分之间存在显著相关性（P < 0.05）。
PTNS对治疗难治性急迫性尿失禁有用，在采取激进手术之前至少应将其视为一种治疗选择，因为在接受PTNS治疗的难治性急迫性尿失禁患者中，排尿和生活质量变量存在显著且可量化的相关性。在生活质量改善之前，患者每天使用的尿垫必须减少≥两片，这可能是急迫性尿失禁患者成功治疗的最佳定义。
