Vandoninck Vera, Van Balken Michael R, Finazzi Agró E, Petta Filomena, Caltagirone Carlo, Heesakkers John P F A, Kiemeney Lambertus A L M, Debruyne Frans M J, Bemelmans Bart L H
Department of Urology, University Medical Centre Nijmegen, The Netherlands.
Neurourol Urodyn. 2003;22(1):17-23. doi: 10.1002/nau.10036.
The objective of this study was to evaluate the effect of posterior tibial nerve stimulation (PTNS) for treatment of urge incontinence.
In a prospective multicentre study, 35 patients with complaints of urge incontinence underwent 12 weekly sessions of PTNS at one of five sites in the Netherlands and one site in Italy. Frequency/volume charts and I-QoL and SF-36 questionnaires were completed at 0 and 12 weeks. Success was analysed by using subjective and objective criteria. Overall subjective success was defined as the willingness to continue treatment, whereas objective success was defined as a significant decrease (to<50%) in total number of leakage episodes.
Twenty-two patients (63%) reported a subjective success. Twenty-four patients (70%) showed a 50% or greater reduction in total number of leakage episodes. Sixteen (46%) of these-patients were completely cured (i.e., no leakage episodes) after 12 sessions. Quality of life parameters improved significantly.
We conclude that posterior tibial nerve stimulation is an effective, minimally invasive option for treatment of patients with complaints of urge incontinence, as improvement was seen in subjective as well as objective parameters.
本研究的目的是评估胫后神经刺激（PTNS）治疗急迫性尿失禁的效果。
在一项前瞻性多中心研究中，35例主诉急迫性尿失禁的患者在荷兰的5个地点之一和意大利的1个地点接受了为期12周的PTNS治疗。在第0周和第12周完成频率/尿量图表以及I-QoL和SF-36问卷调查。通过主观和客观标准分析治疗效果。总体主观成功定义为愿意继续治疗，而客观成功定义为漏尿发作总数显著减少（至<50%）。
22例患者（63%）报告主观成功。24例患者（70%）漏尿发作总数减少了50%或更多。其中16例（46%）患者在接受12次治疗后完全治愈（即无漏尿发作）。生活质量参数显著改善。
我们得出结论，胫后神经刺激是治疗主诉急迫性尿失禁患者的一种有效、微创的选择，因为主观和客观参数均有改善。
