肾小管间质损伤与肾衰竭进展
Tubulointerstitial damage and progression of renal failure.
作者信息
Rodríguez-Iturbe Bernardo, Johnson Richard J, Herrera-Acosta Jaime
机构信息
Hospital Universitario and Universidad del Zulia, Maracaibo, Venezuela.
出版信息
Kidney Int Suppl. 2005 Dec(99):S82-6. doi: 10.1111/j.1523-1755.2005.09915.x.
Abstract
The present work reviews the mechanisms and close association between glomerular and tubular damage and its relationship to renal functional impairment. In addition, we present an overview of the pathways involved in the progression of tubulointerstitial fibrosis and a brief summary of the treatments used to retard the progression to end-stage renal failure.
摘要
本研究综述了肾小球和肾小管损伤之间的机制及密切关联，以及其与肾功能损害的关系。此外，我们还概述了肾小管间质纤维化进展过程中涉及的途径，并简要总结了用于延缓终末期肾衰竭进展的治疗方法。
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