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使用1320纳米钕钇铝石榴石激光对大隐静脉进行腔内治疗比使用940纳米二极管激光产生的副作用更少。

Endovenous treatment of the great saphenous vein using a 1,320 nm Nd:YAG laser causes fewer side effects than using a 940 nm diode laser.

作者信息

Proebstle Thomas M, Moehler Thomas, Gül Doendue, Herdemann Sylvia

机构信息

Department of Dermatology, University of Heidelberg, Germany.

出版信息

Dermatol Surg. 2005 Dec;31(12):1678-83; discussion 1683-4. doi: 10.2310/6350.2005.31308.

Abstract

BACKGROUND

Limited data are available about treatment-related side effects with respect to laser wavelength in endovenous laser treatment (ELT) of the great saphenous vein (GSV).

OBJECTIVE

To compare the results and side effects of a 940 nm diode and a 1,320 nm neodymium:yttium-aluminum-garnet (Nd:YAG) laser.

METHODS

Three patient cohorts (A, B, and C) received ELT of the GSV using a 940 nm diode laser at 15 W (group A) or 30 W (group B) or using a 1,320 nm laser at 8 W (group C). In all cases, energy was administered continuously with constant pullback of the laser fiber under perivenous tumescent local anesthesia.

RESULTS

The GSVs of group A (n = 113), group B (n = 136), and group C (n = 33) received ELT. An average linear endovenous energy density of 24, 63, and 62 J/cm and an average endovenous fluence equivalent of 12, 30, and 33 J/cm2 were administered to the vein. Occlusion rates were 95% (group A), 100% (group B), and 100% (group C) at day 1 after ELT and 90.3% (group A), 100% (group B), and 97% (group C) at 3 months after ELT. With the 1,320 nm laser ELT (group C), treatment-related pain (50%) and the need for analgesics (36%) were significantly reduced (p < .005) in comparison with treatment-related pain (81%) and the need for analgesics (67%) after the 30 W 940 nm laser ELT (group B). Ecchymosis was also significantly reduced (p < .05) in group C (1,320 nm) compared with group B (30 W, 940 nm).

CONCLUSION

ELT of the GSV using a 1,320 nm Nd:YAG laser causes fewer side effects compared with 940 nm diode laser ELT.

摘要

背景

关于大隐静脉腔内激光治疗(ELT)中激光波长与治疗相关副作用的可用数据有限。

目的

比较940nm二极管激光和1320nm钕:钇铝石榴石(Nd:YAG)激光的治疗结果和副作用。

方法

三个患者队列(A、B和C)接受了大隐静脉的腔内激光治疗,A组使用15W的940nm二极管激光,B组使用30W的940nm二极管激光,C组使用8W的1320nm激光。在所有病例中,在静脉周围肿胀局部麻醉下,随着激光光纤的持续回撤连续给予能量。

结果

A组(n = 113)、B组(n = 136)和C组(n = 33)的大隐静脉接受了腔内激光治疗。静脉接受的平均线性腔内能量密度分别为24、63和62 J/cm,平均腔内能量通量当量分别为12、30和33 J/cm²。腔内激光治疗后第1天的闭塞率分别为95%(A组)、100%(B组)和100%(C组),腔内激光治疗后3个月的闭塞率分别为90.3%(A组)、100%(B组)和97%(C组)。与30W 940nm激光腔内激光治疗(B组)后的治疗相关疼痛(81%)和镇痛需求(67%)相比,1320nm激光腔内激光治疗(C组)的治疗相关疼痛(50%)和镇痛需求(36%)显著降低(p < .005)。与B组(30W,940nm)相比,C组(1320nm)的瘀斑也显著减少(p < .05)。

结论

与940nm二极管激光腔内激光治疗相比,使用1320nm Nd:YAG激光进行大隐静脉腔内激光治疗产生的副作用更少。

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