自体非培养黑素细胞-角质形成细胞移植治疗生殖器白癜风。
Genital vitiligo treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.
作者信息
Mulekar Sanjeev V, Al Issa Ahmed, Al Eisa Abdullah, Asaad Marwan
机构信息
National Center for Vitiligo and Psoriasis, Riyadh, Saudi Arabia.
出版信息
Dermatol Surg. 2005 Dec;31(12):1737-9; discussion 1740. doi: 10.2310/6350.2005.31324.
BACKGROUND
Genital vitiligo is common and has a deleterious effect on the psychosexual function of patients. It is well known that glabrous skin (non-hair-bearing skin such as below the ankles, genitalia, lips, distal ends of fingers) rarely responds to the therapy unless it has some residual pigment.
OBJECTIVE
The objective was to report genital vitiligo treated successfully by autologous, noncultured, melanocyte-keratinocyte cell transplantation.
METHODS
Three cases of clinically stable genital vitiligo were treated by autologous, noncultured melanocyte-keratinocyte cell transplantation.
RESULTS
All lesions treated repigmented almost completely. All patients were very satisfied with the excellent cosmetic results.
CONCLUSION
Autologous, noncultured melanocyte-keratinocyte cell transplantation may be an effective surgical treatment for management of genital vitiligo.
背景
生殖器白癜风很常见，对患者的性心理功能有不良影响。众所周知，无毛皮肤（如脚踝以下、生殖器、嘴唇、手指末端等无毛发的皮肤）除非有一些残留色素，否则很少对治疗有反应。
目的
报告通过自体非培养黑素细胞-角质形成细胞移植成功治疗生殖器白癜风的情况。
方法
对3例临床稳定的生殖器白癜风患者采用自体非培养黑素细胞-角质形成细胞移植进行治疗。
结果
所有治疗的皮损几乎完全复色。所有患者对极佳的美容效果非常满意。
结论
自体非培养黑素细胞-角质形成细胞移植可能是治疗生殖器白癜风的一种有效手术方法。
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