Ducos Eric, Fraysse Staffan, Boutry Marc
Unité de Biochimie Physiologique, Institut des Sciences de la Vie, Université Catholique de Louvain, Croix du Sud, 5, B-1348 Louvain-la-Neuve, Belgium.
FEBS Lett. 2005 Dec 19;579(30):6791-5. doi: 10.1016/j.febslet.2005.11.014. Epub 2005 Nov 28.
In plants, the ABC transporter PDR (pleiotropic drug resistance) subfamily is composed of approximately 15 genes, few of which have been analyzed. We have identified NtPDR3, a Nicotiana tabacum PDR gene belonging to a cluster for which no functional data was previously available. NtPDR3 was found to be induced in suspension cells treated with methyl jasmonate, salicylic acid, 1-naphthalene acetic acid, or cembrene, a macrocyclic diterpene. In agreement with the identification of a putative iron deficiency element in the NtPDR3 transcription promoter region, we found that iron deficiency in the culture medium induced NtPDR3 expression, thus suggesting a new function of the PDR transporter family.
在植物中，ABC转运蛋白PDR（多效性药物抗性）亚家族由大约15个基因组成，其中很少有基因经过分析。我们鉴定出了NtPDR3，它是烟草的一个PDR基因，属于一个此前没有功能数据的基因簇。我们发现，用茉莉酸甲酯、水杨酸、1-萘乙酸或大戟二萜西松烯处理悬浮细胞时，NtPDR3会被诱导表达。与在NtPDR3转录启动子区域鉴定出一个假定的缺铁元件一致，我们发现培养基中的缺铁会诱导NtPDR3表达，从而提示了PDR转运蛋白家族的一个新功能。
