Schulberg Herbert C, Lee Pamela W, Bruce Martha L, Raue Patrick J, Lefever Jean J, Williams John W, Dietrich Allen J, Nutting Paul A
Weill Medical College of Cornell University, White Plains, NY 10605, USA.
Ann Fam Med. 2005 Nov-Dec;3(6):523-8. doi: 10.1370/afm.377.
We investigated the prevalence, severity, and course of passive and active suicidal ideation occurring in primary care patients with an uncomplicated depressive disorder.
We studied suicidal ideation experienced by patients recruited in 60 primary care practices participating in a randomized controlled trial of depression management. Risk levels associated with suicidal ideation and plans were determined by a 2-stage procedure using pertinent items of the Patient Health Questionnaire-9, the Hopkins Symptom Checklist-20, and the Cornell structured assessment interview and management algorithm.
Of the 761 patients whom physicians judged in need of treatment for a clinical depression, 405 (53%) were experiencing uncomplicated dysthymia, major depression, or both. Among these depressed patients, about 90% had no risk or a low risk of self-harm based on the presence and nature of suicidal ideation; the rest had an intermediate risk. Almost all patients who were initially classified at the no or low risk levels remained at these levels during the subsequent 6 months. The incidence of suicidal ideation at a risk level requiring the physician's immediate attention in this no- or low-risk subgroup was 1.1% at 3 months and 2.6% at 6 months.
Almost all patients with uncomplicated dysthymia, major depression, or both acknowledging suicidal ideation of the minimal risk type when initially assessed maintained this minimal risk status during the subsequent 6 months.
我们调查了患有单纯性抑郁症的初级保健患者中被动和主动自杀意念的患病率、严重程度及病程。
我们研究了参与抑郁症管理随机对照试验的60家初级保健机构招募的患者所经历的自杀意念。使用患者健康问卷-9、霍普金斯症状清单-20的相关条目以及康奈尔结构化评估访谈和管理算法,通过两阶段程序确定与自杀意念及计划相关的风险水平。
在医生判定需要治疗临床抑郁症的761名患者中,405名(53%)患有单纯性心境恶劣、重度抑郁症或两者皆有。在这些抑郁症患者中,根据自杀意念的存在及性质,约90%无自残风险或风险较低;其余患者风险中等。几乎所有最初被归类为无风险或低风险水平的患者在随后6个月内仍维持这些水平。在这个无风险或低风险亚组中,处于需要医生立即关注的风险水平的自杀意念发生率在第3个月时为1.1%,在第6个月时为2.6%。
几乎所有最初评估时承认有最低风险类型自杀意念的单纯性心境恶劣、重度抑郁症或两者皆有的患者,在随后6个月内维持了这种最低风险状态。