Heiner J S, Kerin J F, Schmidt L L, Wu T C
University of California-Los Angeles (UCLA), School of Medicine.
Fertil Steril. 1992 Aug;58(2):373-7. doi: 10.1016/s0015-0282(16)55232-7.
To assess the predictive value of a single serum human chorionic gonadotropin (hCG) measurement obtained on day 14, 15, or 16 after transfer in in vitro fertilization or gamete intrafallopian transfer pregnancies.
Retrospective.
Assisted reproductive technology (ART) programs.
One hundred thirty-four consecutive pregnancies from two ART programs were reviewed.
The incidence of livebirth was only 6% when day 14 to 16 hCG values were less than 100 mIU/mL, but increased to 82% with levels greater than 100 mIU/mL (P less than 0.001). The incidence of livebirth and multiple birth correlated with rising hCG levels. Only 1% (1/71) of pregnancies with serum hCG values greater than 100 mIU/mL was ectopic, and this case was a bilateral (double) ectopic.
A single serum hCG measurement obtained 14 to 16 days after embryo or gamete transfer not only is diagnostic but also has good predictive value for pregnancy outcome.
评估在体外受精或配子输卵管内移植妊娠后第14、15或16天进行的单次血清人绒毛膜促性腺激素（hCG）检测对妊娠结局的预测价值。
回顾性研究。
辅助生殖技术（ART）项目。
对来自两个ART项目的134例连续妊娠进行了回顾。
当第14至16天的hCG值低于100 mIU/mL时，活产率仅为6%，但当hCG水平高于100 mIU/mL时，活产率增至82%（P<0.001）。活产率和多胎妊娠率与hCG水平升高相关。血清hCG值高于100 mIU/mL的妊娠中，只有1%（1/71）为异位妊娠，且该病例为双侧（双）异位妊娠。
在胚胎或配子移植后14至16天进行的单次血清hCG检测不仅具有诊断价值，而且对妊娠结局具有良好的预测价值。
