Müller-Schoop J, Gerber N, Knoblauch M
Schweiz Med Wochenschr. 1977 Apr 16;107(15):523-5.
Personal observations have confirmed the frequent association of HB-infection with certain forms of vasculitis. 4 of 11 patients with polyarteritis nodosa were repeatedly found to be HBs-Ag positive and had chronic hepatitis of varying severity. In patients with giant cell arteritis (polymyalgia rheumatica and temporal arteritis) anti-HBs was found more frequently than in controls, especially when examined within 6 months after onset of symptoms (7 of 20 equal 35% had anti-HBs, versus 6% of controls). Several lines of evidence point to the important role played by circulating HBs-Ag/anti-HBs complexes in the development of HB-associated vasculitis.
个人观察结果证实,乙肝感染与某些形式的血管炎常有关联。11例结节性多动脉炎患者中有4例多次被发现乙肝表面抗原呈阳性,并患有不同严重程度的慢性肝炎。在巨细胞动脉炎(风湿性多肌痛和颞动脉炎)患者中,抗乙肝表面抗体的检出率高于对照组,尤其是在症状出现后6个月内进行检查时(20例中有7例,即35%有抗乙肝表面抗体,而对照组为6%)。有几条证据表明,循环中的乙肝表面抗原/抗乙肝表面抗体复合物在乙肝相关血管炎的发生中起重要作用。