Eandi Chiara M, Ober Michael, Iranmanesh Reza, Peiretti Enrico, Yannuzzi Lawrence A
The LuEsther T. Mertz Retina Research Center of Manhattan Eye, Ear and Throat Hospital, New York, NY 10021, USA.
Retina. 2005 Dec;25(8):989-93. doi: 10.1097/00006982-200512000-00006.
To describe fundus autofluorescence (FAF) in a series of patients with acute central serous chorioretinopathy (CSC).
Nine eyes of six patients with acute CSC were evaluated with fluorescein angiography (FA) and FAF imaging to evaluate the nature of the focal retinal pigment epithelial (RPE) leak evident with FA.
All nine eyes in this series demonstrated hypo-autofluorescence corresponding precisely to the site of the focal RPE leak seen on FA.
In this group of patients, the acute focal RPE leaks seen with FA corresponded precisely to an area of hypo-autofluorescence imaged with FAF. This observation supports the concept that a mechanical defect or absence of the RPE accounts for the leakage from the inner choroid to the sub-neurosensory space in CSC. FAF is also a useful noninvasive diagnostic adjunct to identify the focal RPE leak in patients with acute CSC.
描述一系列急性中心性浆液性脉络膜视网膜病变（CSC）患者的眼底自发荧光（FAF）情况。
对6例急性CSC患者的9只眼进行荧光素血管造影（FA）和FAF成像评估，以评价FA显示的局灶性视网膜色素上皮（RPE）渗漏的性质。
该系列中的所有9只眼均表现出自发荧光减低，与FA上所见的局灶性RPE渗漏部位精确对应。
在这组患者中，FA所见的急性局灶性RPE渗漏与FAF成像的自发荧光减低区域精确对应。这一观察结果支持了这样的概念，即RPE的机械性缺陷或缺失是CSC中脉络膜内层渗漏至神经感觉下间隙的原因。FAF也是识别急性CSC患者局灶性RPE渗漏的一种有用的非侵入性诊断辅助手段。
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