分析类风湿性关节炎患者抑郁状态变化的可靠性。
Analyzing reliability of change in depression among persons with rheumatoid arthritis.
作者信息
Martens Matthew P, Vandyke Melanie, Parker Jerry C, Smarr Karen L, Hewett James E, Hewett John E, Walker Sara E
机构信息
Harry S. Truman Memorial Veterans' Hospital, and the University of Missouri School of Medicine, Columbia, Missouri 65201, USA.
出版信息
Arthritis Rheum. 2005 Dec 15;53(6):973-8. doi: 10.1002/art.21578.
OBJECTIVE
To examine several methods of determining reliability of change constructs in depressive symptoms in patients with rheumatoid arthritis (RA) and to demonstrate the strengths, weaknesses, and uses of each method.
METHODS
Data were analyzed from a cohort of 54 persons with RA who participated in a combined behavioral/pharmacologic intervention of 15 months duration. These longitudinal data were used to examine 3 methodologies for assessing the reliability of change for various measures of depression. The specific methodologies involved the calculations of reliable change, sensitivity to change, and reliability of the change score.
RESULTS
The analyses demonstrated differences in reliability of change performance across the various depression measures, which suggest that no single measure of depression for persons with RA should be considered superior in all contexts.
CONCLUSION
The findings highlight the value of utilizing reliability of change constructs when examining changes in depressive symptoms over time.
目的
研究几种确定类风湿关节炎（RA）患者抑郁症状变化结构可靠性的方法，并展示每种方法的优缺点及用途。
方法
对54名参与为期15个月的行为/药物联合干预的RA患者队列数据进行分析。这些纵向数据用于检验评估各种抑郁测量指标变化可靠性的3种方法。具体方法包括可靠变化的计算、对变化的敏感性以及变化分数的可靠性。
结果
分析表明，不同抑郁测量指标的变化表现可靠性存在差异，这表明在所有情况下，不应认为RA患者的单一抑郁测量指标都是 superior 的。
结论
研究结果凸显了在检查抑郁症状随时间变化时利用变化结构可靠性的价值。
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