Kim Do Young, Kim Jie Hyun, Chon Chae Yoon, Han Kwang-Hyub, Ahn Sang Hoon, Kim Ja Kyung, Paik Yong Han, Lee Kwan Sik, Moon Young Myoung
Department of Internal Medicine, Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea.
Liver Int. 2005 Dec;25(6):1197-201. doi: 10.1111/j.1478-3231.2005.01176.x.
Rapid and accurate diagnosis of spontaneous bacterial peritonitis (SBP) is mandatory for timely treatment in cirrhotic patients. The purpose of this study was to assess the usefulness of two different reagent strips, the UriSCAN and the Multistix10SG, for the rapid bedside diagnosis of SBP.
A total of 75 paracenteses in 53 cirrhotic patients with ascites were performed. All ascitic fluid was analyzed with the two reagent strips, and compared with the manual cell count with differential and ascitic fluid culture. SBP was defined as an ascitic polymorphonuclear cell count > or =250/mm3.
SBP was diagnosed in 18 of the 75 samples. If we considered the positive UriSCAN result of 2 or more, the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were all 100%. When we considered the positive UriSCAN result of 3, the sensitivity, specificity, PPV, and NPV were 67%, 100%, 100%, and 89%, respectively. When we considered the positive Multistix10SG result of 3, the sensitivity, specificity, PPV, and NPV were 50%, 100%, 100%, and 87%, respectively.
Urine reagent strip might be useful for rapid and accurate diagnosis of SBP in cirrhotic patients with ascites.
对于肝硬化患者的及时治疗而言，快速准确地诊断自发性细菌性腹膜炎（SBP）至关重要。本研究的目的是评估两种不同的试剂条UriSCAN和Multistix10SG在SBP床边快速诊断中的实用性。
对53例肝硬化腹水患者共进行了75次腹腔穿刺。所有腹水均用这两种试剂条进行分析，并与手工细胞计数及分类和腹水培养结果进行比较。SBP定义为腹水多形核细胞计数≥250/mm³。
75份样本中有18份诊断为SBP。如果将UriSCAN阳性结果判定为2或更高，其敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）均为100%。当将UriSCAN阳性结果判定为3时，敏感性、特异性、PPV和NPV分别为67%、100%、100%和89%。当将Multistix10SG阳性结果判定为3时，敏感性、特异性、PPV和NPV分别为50%、100%、100%和87%。
尿试剂条可能有助于对肝硬化腹水患者的SBP进行快速准确的诊断。
