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壳聚糖的新型衍生物及其体外抗真菌活性

Novel derivatives of chitosan and their antifungal activities in vitro.

作者信息

Guo Zhanyong, Chen Rong, Xing Ronge, Liu Song, Yu Huahua, Wang Pibo, Li Cuiping, Li Pengcheng

机构信息

Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, China.

出版信息

Carbohydr Res. 2006 Feb 27;341(3):351-4. doi: 10.1016/j.carres.2005.11.002. Epub 2005 Dec 15.

Abstract

Three kinds of Schiff bases of carboxymethyl chitosan (CMCTS) were prepared, and their antifungal activities were assessed according to Jasso de Rodríguez's method. The results indicated that 2-(2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HNCMCTS) and 2-(5-chloro-2-hydroxybenzylideneamino)-6-carboxymethylchitosan (HCCMCTS) had better inhibitory effects than those of chitosan or CMCTS against Fusarium oxysporium f. sp. vasinfectum, Alternaria solani, and Valsa mali.

摘要

制备了三种羧甲基壳聚糖(CMCTS)席夫碱,并根据雅索·德·罗德里格斯的方法评估了它们的抗真菌活性。结果表明,2-(2-羟基亚苄基氨基)-6-羧甲基壳聚糖(HNCMCTS)和2-(5-氯-2-羟基亚苄基氨基)-6-羧甲基壳聚糖(HCCMCTS)对尖孢镰刀菌枯萎专化型、茄链格孢和苹果黑腐皮壳菌的抑制效果比壳聚糖或CMCTS更好。

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