丙酮、异丙醇和丁醇的生物合成：拜氏梭菌（同义名：丁酸梭菌）和橙色溶纤维丁酸弧菌。
Acetone, Isopropanol, and Butanol Production by Clostridium beijerinckii (syn. Clostridium butylicum) and Clostridium aurantibutyricum.
机构信息
Department of Anaerobic Microbiology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061.
出版信息
Appl Environ Microbiol. 1983 Mar;45(3):1160-3. doi: 10.1128/aem.45.3.1160-1163.1983.
Abstract
Thirty-four strains representing 15 species of anaerobic bacteria were screened for acetone, isopropanol, and n-butanol (solvent) production. Under our culture conditions, several strains of Clostridium beijerinckii and C. aurantibutyricum produced at least 40 mM n-butanol (C. acetobutylicum strains produced up to 41 mM n-butanol under similar conditions). Both solvent-producing and non-solvent-producing strains of C. beijerinckii have high DNA homology with a reference strain of C. beijerinckii. Strains labeled "Clostridium butylicum" are phenotypically similar to C. beijerinckii and showed at least 78% DNA homology to a reference strain of C. beijerinckii. Therefore, these "C. butylicum" strains are members of C. beijerinckii. An earlier DNA homology study has shown that C. beijerinckii, C. aurantibutyricum, and C. acetobutylicum are distinct species.
摘要
34 株代表 15 种厌氧菌的菌株被筛选用于生产丙酮、异丙醇和正丁醇（溶剂）。在我们的培养条件下，几株拜氏梭菌和橙色丁酸梭菌至少产生了 40mM 的正丁醇（在类似条件下，丙酮丁醇梭菌菌株最多可产生 41mM 的正丁醇）。无论是产溶剂菌株还是非产溶剂菌株，拜氏梭菌的 DNA 同源性都与参考菌株的拜氏梭菌高度相似。标记为“丁酸梭菌”的菌株在表型上与拜氏梭菌相似，与拜氏梭菌的参考菌株的 DNA 同源性至少为 78%。因此，这些“丁酸梭菌”菌株是拜氏梭菌的成员。早期的 DNA 同源性研究表明，拜氏梭菌、橙色丁酸梭菌和丙酮丁醇梭菌是不同的物种。
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